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Induction of autophagy by spermidine promotes longevity.
Eisenberg T, Knauer H, Schauer A, Büttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, Fussi H, Deszcz L, Hartl R, Schraml E, Criollo A, Megalou E, Weiskopf D, Laun P, Heeren G, Breitenbach M, Grubeck-Loebenstein B, Herker E, Fahrenkrog B, Fröhlich KU, Sinner F, Tavernarakis N, Minois N, Kroemer G, Madeo F. Eisenberg T, et al. Among authors: laun p. Nat Cell Biol. 2009 Nov;11(11):1305-14. doi: 10.1038/ncb1975. Epub 2009 Oct 4. Nat Cell Biol. 2009. PMID: 19801973
A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis.
Büttner S, Ruli D, Vögtle FN, Galluzzi L, Moitzi B, Eisenberg T, Kepp O, Habernig L, Carmona-Gutierrez D, Rockenfeller P, Laun P, Breitenbach M, Khoury C, Fröhlich KU, Rechberger G, Meisinger C, Kroemer G, Madeo F. Büttner S, et al. Among authors: laun p. EMBO J. 2011 Jun 14;30(14):2779-92. doi: 10.1038/emboj.2011.197. EMBO J. 2011. PMID: 21673659 Free PMC article.
The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1.
Heeren G, Rinnerthaler M, Laun P, von Seyerl P, Kössler S, Klinger H, Hager M, Bogengruber E, Jarolim S, Simon-Nobbe B, Schüller C, Carmona-Gutierrez D, Breitenbach-Koller L, Mück C, Jansen-Dürr P, Criollo A, Kroemer G, Madeo F, Breitenbach M. Heeren G, et al. Among authors: laun p. Aging (Albany NY). 2009 Jul 13;1(7):622-36. doi: 10.18632/aging.100065. Aging (Albany NY). 2009. PMID: 20157544 Free PMC article.
MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria.
Rinnerthaler M, Jarolim S, Heeren G, Palle E, Perju S, Klinger H, Bogengruber E, Madeo F, Braun RJ, Breitenbach-Koller L, Breitenbach M, Laun P. Rinnerthaler M, et al. Among authors: laun p. Biochim Biophys Acta. 2006 May-Jun;1757(5-6):631-8. doi: 10.1016/j.bbabio.2006.05.022. Epub 2006 May 20. Biochim Biophys Acta. 2006. PMID: 16806052 Free article.
Introduction.
Breitenbach M, Laun P, Jazwinski SM. Breitenbach M, et al. Among authors: laun p. Subcell Biochem. 2012;57:1-12. doi: 10.1007/978-94-007-2561-4_1. Subcell Biochem. 2012. PMID: 22094415 Review.
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