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Extraepitopic compensatory substitutions partially restore fitness to simian immunodeficiency virus variants that escape from an immunodominant cytotoxic-T-lymphocyte response.
Friedrich TC, Frye CA, Yant LJ, O'Connor DH, Kriewaldt NA, Benson M, Vojnov L, Dodds EJ, Cullen C, Rudersdorf R, Hughes AL, Wilson N, Watkins DI. Friedrich TC, et al. Among authors: vojnov l. J Virol. 2004 Mar;78(5):2581-5. doi: 10.1128/jvi.78.5.2581-2585.2004. J Virol. 2004. PMID: 14963161 Free PMC article.
Consequences of cytotoxic T-lymphocyte escape: common escape mutations in simian immunodeficiency virus are poorly recognized in naive hosts.
Friedrich TC, McDermott AB, Reynolds MR, Piaskowski S, Fuenger S, De Souza IP, Rudersdorf R, Cullen C, Yant LJ, Vojnov L, Stephany J, Martin S, O'Connor DH, Wilson N, Watkins DI. Friedrich TC, et al. Among authors: vojnov l. J Virol. 2004 Sep;78(18):10064-73. doi: 10.1128/JVI.78.18.10064-10073.2004. J Virol. 2004. PMID: 15331739 Free PMC article.
Pol-specific CD8+ T cells recognize simian immunodeficiency virus-infected cells prior to Nef-mediated major histocompatibility complex class I downregulation.
Sacha JB, Chung C, Reed J, Jonas AK, Bean AT, Spencer SP, Lee W, Vojnov L, Rudersdorf R, Friedrich TC, Wilson NA, Lifson JD, Watkins DI. Sacha JB, et al. Among authors: vojnov l. J Virol. 2007 Nov;81(21):11703-12. doi: 10.1128/JVI.00926-07. Epub 2007 Aug 15. J Virol. 2007. PMID: 17699580 Free PMC article.
Recombinant yellow fever vaccine virus 17D expressing simian immunodeficiency virus SIVmac239 gag induces SIV-specific CD8+ T-cell responses in rhesus macaques.
Bonaldo MC, Martins MA, Rudersdorf R, Mudd PA, Sacha JB, Piaskowski SM, Costa Neves PC, Veloso de Santana MG, Vojnov L, Capuano S 3rd, Rakasz EG, Wilson NA, Fulkerson J, Sadoff JC, Watkins DI, Galler R. Bonaldo MC, et al. Among authors: vojnov l. J Virol. 2010 Apr;84(7):3699-706. doi: 10.1128/JVI.02255-09. Epub 2010 Jan 20. J Virol. 2010. PMID: 20089645 Free PMC article.
GagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo.
Vojnov L, Martins MA, Almeida JR, Ende Z, Rakasz EG, Reynolds MR, Leon EJ, Weisgrau KL, Burwitz BJ, Folkvord JM, de Santana MG, Neves PC, Connick E, Skinner PJ, Gostick E, O'Connor DH, Wilson NA, Bonaldo MC, Galler R, Price DA, Douek DC, Watkins DI. Vojnov L, et al. PLoS One. 2011;6(8):e23515. doi: 10.1371/journal.pone.0023515. Epub 2011 Aug 26. PLoS One. 2011. PMID: 21887264 Free PMC article.
Reversion of CTL escape-variant immunodeficiency viruses in vivo.
Friedrich TC, Dodds EJ, Yant LJ, Vojnov L, Rudersdorf R, Cullen C, Evans DT, Desrosiers RC, Mothé BR, Sidney J, Sette A, Kunstman K, Wolinsky S, Piatak M, Lifson J, Hughes AL, Wilson N, O'Connor DH, Watkins DI. Friedrich TC, et al. Among authors: vojnov l. Nat Med. 2004 Mar;10(3):275-81. doi: 10.1038/nm998. Epub 2004 Feb 15. Nat Med. 2004. PMID: 14966520
66 results