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Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L.
Hessell AJ, Rakasz EG, Tehrani DM, Huber M, Weisgrau KL, Landucci G, Forthal DN, Koff WC, Poignard P, Watkins DI, Burton DR. Hessell AJ, et al. Among authors: burton dr. J Virol. 2010 Feb;84(3):1302-13. doi: 10.1128/JVI.01272-09. Epub 2009 Nov 11. J Virol. 2010. PMID: 19906907 Free PMC article.
Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120.
Moore JP, Cao Y, Qing L, Sattentau QJ, Pyati J, Koduri R, Robinson J, Barbas CF 3rd, Burton DR, Ho DD. Moore JP, et al. Among authors: burton dr. J Virol. 1995 Jan;69(1):101-9. doi: 10.1128/JVI.69.1.101-109.1995. J Virol. 1995. PMID: 7527081 Free PMC article.
Human monoclonal antibodies: recent achievements.
Burton DR, Barbas CF 3rd. Burton DR, et al. Hosp Pract (Off Ed). 1994 Nov 15;29(11):111, 114-6, 119 passim. doi: 10.1080/21548331.1994.11443111. Hosp Pract (Off Ed). 1994. PMID: 7962228 Review.
660 results