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Plasmepsin 4-deficient Plasmodium berghei are virulence attenuated and induce protective immunity against experimental malaria.
Spaccapelo R, Janse CJ, Caterbi S, Franke-Fayard B, Bonilla JA, Syphard LM, Di Cristina M, Dottorini T, Savarino A, Cassone A, Bistoni F, Waters AP, Dame JB, Crisanti A. Spaccapelo R, et al. Am J Pathol. 2010 Jan;176(1):205-17. doi: 10.2353/ajpath.2010.090504. Epub 2009 Dec 17. Am J Pathol. 2010. PMID: 20019192 Free PMC article.
Evidence of tRNA cleavage in apicomplexan parasites: Half-tRNAs as new potential regulatory molecules of Toxoplasma gondii and Plasmodium berghei.
Galizi R, Spano F, Giubilei MA, Capuccini B, Magini A, Urbanelli L, Ogawa T, Dubey JP, Spaccapelo R, Emiliani C, Di Cristina M. Galizi R, et al. Among authors: spaccapelo r. Mol Biochem Parasitol. 2013 Apr;188(2):99-108. doi: 10.1016/j.molbiopara.2013.03.003. Epub 2013 Apr 1. Mol Biochem Parasitol. 2013. PMID: 23557708
Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance.
Lin JW, Spaccapelo R, Schwarzer E, Sajid M, Annoura T, Deroost K, Ravelli RB, Aime E, Capuccini B, Mommaas-Kienhuis AM, O'Toole T, Prins F, Franke-Fayard BM, Ramesar J, Chevalley-Maurel S, Kroeze H, Koster AJ, Tanke HJ, Crisanti A, Langhorne J, Arese P, Van den Steen PE, Janse CJ, Khan SM. Lin JW, et al. Among authors: spaccapelo r. J Exp Med. 2015 Jun 1;212(6):893-903. doi: 10.1084/jem.20141731. Epub 2015 May 4. J Exp Med. 2015. PMID: 25941254 Free PMC article.
Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins.
Pasini EM, Braks JA, Fonager J, Klop O, Aime E, Spaccapelo R, Otto TD, Berriman M, Hiss JA, Thomas AW, Mann M, Janse CJ, Kocken CH, Franke-Fayard B. Pasini EM, et al. Among authors: spaccapelo r. Mol Cell Proteomics. 2013 Feb;12(2):426-48. doi: 10.1074/mcp.M112.021238. Epub 2012 Nov 28. Mol Cell Proteomics. 2013. PMID: 23197789 Free PMC article.
71 results