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Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors.
EMBO Mol Med. 2009 Sep;1(6-7):315-22. doi: 10.1002/emmm.200900041.
EMBO Mol Med. 2009.
PMID: 20049735
Free PMC article.
PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors.
Dedes KJ, Wetterskog D, Mendes-Pereira AM, Natrajan R, Lambros MB, Geyer FC, Vatcheva R, Savage K, Mackay A, Lord CJ, Ashworth A, Reis-Filho JS.
Dedes KJ, et al. Among authors: mendes pereira am.
Sci Transl Med. 2010 Oct 13;2(53):53ra75. doi: 10.1126/scitranslmed.3001538.
Sci Transl Med. 2010.
PMID: 20944090
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NLK is a novel therapeutic target for PTEN deficient tumour cells.
Mendes-Pereira AM, Lord CJ, Ashworth A.
Mendes-Pereira AM, et al.
PLoS One. 2012;7(10):e47249. doi: 10.1371/journal.pone.0047249. Epub 2012 Oct 29.
PLoS One. 2012.
PMID: 23144700
Free PMC article.
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Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen.
Mendes-Pereira AM, Sims D, Dexter T, Fenwick K, Assiotis I, Kozarewa I, Mitsopoulos C, Hakas J, Zvelebil M, Lord CJ, Ashworth A.
Mendes-Pereira AM, et al.
Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2730-5. doi: 10.1073/pnas.1018872108. Epub 2011 Apr 11.
Proc Natl Acad Sci U S A. 2012.
PMID: 21482774
Free PMC article.
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Functional viability profiles of breast cancer.
Brough R, Frankum JR, Sims D, Mackay A, Mendes-Pereira AM, Bajrami I, Costa-Cabral S, Rafiq R, Ahmad AS, Cerone MA, Natrajan R, Sharpe R, Shiu KK, Wetterskog D, Dedes KJ, Lambros MB, Rawjee T, Linardopoulos S, Reis-Filho JS, Turner NC, Lord CJ, Ashworth A.
Brough R, et al. Among authors: mendes pereira am.
Cancer Discov. 2011 Aug;1(3):260-73. doi: 10.1158/2159-8290.CD-11-0107. Epub 2011 Aug 2.
Cancer Discov. 2011.
PMID: 21984977
Free PMC article.
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Synthetic lethal targeting of PTEN-deficient cancer cells using selective disruption of polynucleotide kinase/phosphatase.
Mereniuk TR, El Gendy MA, Mendes-Pereira AM, Lord CJ, Ghosh S, Foley E, Ashworth A, Weinfeld M.
Mereniuk TR, et al. Among authors: mendes pereira am.
Mol Cancer Ther. 2013 Oct;12(10):2135-44. doi: 10.1158/1535-7163.MCT-12-1093. Epub 2013 Jul 24.
Mol Cancer Ther. 2013.
PMID: 23883586
Free PMC article.
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High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing.
Sims D, Mendes-Pereira AM, Frankum J, Burgess D, Cerone MA, Lombardelli C, Mitsopoulos C, Hakas J, Murugaesu N, Isacke CM, Fenwick K, Assiotis I, Kozarewa I, Zvelebil M, Ashworth A, Lord CJ.
Sims D, et al. Among authors: mendes pereira am.
Genome Biol. 2011 Oct 21;12(10):R104. doi: 10.1186/gb-2011-12-10-r104.
Genome Biol. 2011.
PMID: 22018332
Free PMC article.
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Functional screening reveals HORMAD1-driven gene dependencies associated with translesion synthesis and replication stress tolerance.
Tarantino D, Walker C, Weekes D, Pemberton H, Davidson K, Torga G, Frankum J, Mendes-Pereira AM, Prince C, Ferro R, Brough R, Pettitt SJ, Lord CJ, Grigoriadis A, Nj Tutt A.
Tarantino D, et al. Among authors: mendes pereira am.
Oncogene. 2022 Aug;41(32):3969-3977. doi: 10.1038/s41388-022-02369-9. Epub 2022 Jun 29.
Oncogene. 2022.
PMID: 35768547
Free PMC article.
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