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Rational design of cationic lipids for siRNA delivery.
Nat Biotechnol. 2010 Feb;28(2):172-6. doi: 10.1038/nbt.1602. Epub 2010 Jan 17.
Nat Biotechnol. 2010.
PMID: 20081866
RNAi-mediated gene silencing in non-human primates.
Zimmermann TS, Lee AC, Akinc A, Bramlage B, Bumcrot D, Fedoruk MN, Harborth J, Heyes JA, Jeffs LB, John M, Judge AD, Lam K, McClintock K, Nechev LV, Palmer LR, Racie T, Röhl I, Seiffert S, Shanmugam S, Sood V, Soutschek J, Toudjarska I, Wheat AJ, Yaworski E, Zedalis W, Koteliansky V, Manoharan M, Vornlocher HP, MacLachlan I.
Zimmermann TS, et al. Among authors: jeffs lb.
Nature. 2006 May 4;441(7089):111-4. doi: 10.1038/nature04688. Epub 2006 Mar 26.
Nature. 2006.
PMID: 16565705
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Lipid encapsulation enables the effective systemic delivery of polyplex plasmid DNA.
Heyes J, Palmer L, Chan K, Giesbrecht C, Jeffs L, MacLachlan I.
Heyes J, et al.
Mol Ther. 2007 Apr;15(4):713-20. doi: 10.1038/sj.mt.6300101. Epub 2007 Feb 13.
Mol Ther. 2007.
PMID: 17299407
Free article.
Item in Clipboard
Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs.
Morrissey DV, Lockridge JA, Shaw L, Blanchard K, Jensen K, Breen W, Hartsough K, Machemer L, Radka S, Jadhav V, Vaish N, Zinnen S, Vargeese C, Bowman K, Shaffer CS, Jeffs LB, Judge A, MacLachlan I, Polisky B.
Morrissey DV, et al. Among authors: jeffs lb.
Nat Biotechnol. 2005 Aug;23(8):1002-7. doi: 10.1038/nbt1122. Epub 2005 Jul 24.
Nat Biotechnol. 2005.
PMID: 16041363
Free article.
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A scalable, extrusion-free method for efficient liposomal encapsulation of plasmid DNA.
Jeffs LB, Palmer LR, Ambegia EG, Giesbrecht C, Ewanick S, MacLachlan I.
Jeffs LB, et al.
Pharm Res. 2005 Mar;22(3):362-72. doi: 10.1007/s11095-004-1873-z.
Pharm Res. 2005.
PMID: 15835741
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Postexposure protection of guinea pigs against a lethal ebola virus challenge is conferred by RNA interference.
Geisbert TW, Hensley LE, Kagan E, Yu EZ, Geisbert JB, Daddario-DiCaprio K, Fritz EA, Jahrling PB, McClintock K, Phelps JR, Lee AC, Judge A, Jeffs LB, MacLachlan I.
Geisbert TW, et al. Among authors: jeffs lb.
J Infect Dis. 2006 Jun 15;193(12):1650-7. doi: 10.1086/504267. Epub 2006 May 10.
J Infect Dis. 2006.
PMID: 16703508
Free PMC article.
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Nature and control of chloride transport in insect absorptive epithelia.
Phillips JE, Wiens C, Audsley N, Jeffs L, Bilgen T, Meredith J.
Phillips JE, et al.
J Exp Zool. 1996 Jul 1;275(4):292-9. doi: 10.1002/(SICI)1097-010X(19960701)275:4<292::AID-JEZ7>3.0.CO;2-K.
J Exp Zool. 1996.
PMID: 8759926
Review.
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Toxic properties of Beauveria pigments on erythrocyte membranes.
Jeffs LB, Khachatourians GG.
Jeffs LB, et al.
Toxicon. 1997 Aug;35(8):1351-6. doi: 10.1016/s0041-0101(97)00025-1.
Toxicon. 1997.
PMID: 9278984
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