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Animal disease models generated by genetic engineering of polyamine metabolism.
Jänne J, Alhonen L, Keinänen TA, Pietilä M, Uimari A, Pirinen E, Hyvönen MT, Järvinen A. Jänne J, et al. Among authors: pietila m. J Cell Mol Med. 2005 Oct-Dec;9(4):865-82. doi: 10.1111/j.1582-4934.2005.tb00385.x. J Cell Mol Med. 2005. PMID: 16364196 Free PMC article. Review.
Genetic manipulation of polyamine catabolism in rodents.
Jänne J, Alhonen L, Pietilä M, Keinänen TA, Uimari A, Hyvönen MT, Pirinen E, Järvinen A. Jänne J, et al. Among authors: pietila m. J Biochem. 2006 Feb;139(2):155-60. doi: 10.1093/jb/mvj035. J Biochem. 2006. PMID: 16452302 Review.
Polyamines are required for the initiation of rat liver regeneration.
Alhonen L, Räsänen TL, Sinervirta R, Parkkinen JJ, Korhonen VP, Pietilä M, Jänne J. Alhonen L, et al. Among authors: pietila m. Biochem J. 2002 Feb 15;362(Pt 1):149-53. doi: 10.1042/0264-6021:3620149. Biochem J. 2002. PMID: 11829751 Free PMC article.
Targeted disruption of spermidine/spermine N1-acetyltransferase gene in mouse embryonic stem cells. Effects on polyamine homeostasis and sensitivity to polyamine analogues.
Niiranen K, Pietilä M, Pirttilä TJ, Järvinen A, Halmekytö M, Korhonen VP, Keinänen TA, Alhonen L, Jänne J. Niiranen K, et al. Among authors: pietila m. J Biol Chem. 2002 Jul 12;277(28):25323-8. doi: 10.1074/jbc.M203599200. Epub 2002 May 8. J Biol Chem. 2002. PMID: 12000764 Free article.
Mice with targeted disruption of spermidine/spermine N1-acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging.
Niiranen K, Keinänen TA, Pirinen E, Heikkinen S, Tusa M, Fatrai S, Suppola S, Pietilä M, Uimari A, Laakso M, Alhonen L, Jänne J. Niiranen K, et al. Among authors: pietila m. J Cell Mol Med. 2006 Oct-Dec;10(4):933-45. doi: 10.1111/j.1582-4934.2006.tb00536.x. J Cell Mol Med. 2006. PMID: 17125596 Free article.
Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism.
Pirinen E, Kuulasmaa T, Pietilä M, Heikkinen S, Tusa M, Itkonen P, Boman S, Skommer J, Virkamäki A, Hohtola E, Kettunen M, Fatrai S, Kansanen E, Koota S, Niiranen K, Parkkinen J, Levonen AL, Ylä-Herttuala S, Hiltunen JK, Alhonen L, Smith U, Jänne J, Laakso M. Pirinen E, et al. Among authors: pietila m. Mol Cell Biol. 2007 Jul;27(13):4953-67. doi: 10.1128/MCB.02034-06. Epub 2007 May 7. Mol Cell Biol. 2007. PMID: 17485446 Free PMC article.
190 results