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Impact of EWS-ETS fusion type on disease progression in Ewing's sarcoma/peripheral primitive neuroectodermal tumor: prospective results from the cooperative Euro-E.W.I.N.G. 99 trial.
Le Deley MC, Delattre O, Schaefer KL, Burchill SA, Koehler G, Hogendoorn PC, Lion T, Poremba C, Marandet J, Ballet S, Pierron G, Brownhill SC, Nesslböck M, Ranft A, Dirksen U, Oberlin O, Lewis IJ, Craft AW, Jürgens H, Kovar H. Le Deley MC, et al. Among authors: poremba c. J Clin Oncol. 2010 Apr 20;28(12):1982-8. doi: 10.1200/JCO.2009.23.3585. Epub 2010 Mar 22. J Clin Oncol. 2010. PMID: 20308673
EWS-FLI1 target genes recovered from Ewing's sarcoma chromatin.
Siligan C, Ban J, Bachmaier R, Spahn L, Kreppel M, Schaefer KL, Poremba C, Aryee DN, Kovar H. Siligan C, et al. Among authors: poremba c. Oncogene. 2005 Apr 7;24(15):2512-24. doi: 10.1038/sj.onc.1208455. Oncogene. 2005. PMID: 15735734
EWS-FLI1 suppresses NOTCH-activated p53 in Ewing's sarcoma.
Ban J, Bennani-Baiti IM, Kauer M, Schaefer KL, Poremba C, Jug G, Schwentner R, Smrzka O, Muehlbacher K, Aryee DN, Kovar H. Ban J, et al. Among authors: poremba c. Cancer Res. 2008 Sep 1;68(17):7100-9. doi: 10.1158/0008-5472.CAN-07-6145. Cancer Res. 2008. PMID: 18757425 Free PMC article.
Results of the EICESS-92 Study: two randomized trials of Ewing's sarcoma treatment--cyclophosphamide compared with ifosfamide in standard-risk patients and assessment of benefit of etoposide added to standard treatment in high-risk patients.
Paulussen M, Craft AW, Lewis I, Hackshaw A, Douglas C, Dunst J, Schuck A, Winkelmann W, Köhler G, Poremba C, Zoubek A, Ladenstein R, van den Berg H, Hunold A, Cassoni A, Spooner D, Grimer R, Whelan J, McTiernan A, Jürgens H; European Intergroup Cooperative Ewing's Sarcoma Study-92. Paulussen M, et al. Among authors: poremba c. J Clin Oncol. 2008 Sep 20;26(27):4385-93. doi: 10.1200/JCO.2008.16.5720. J Clin Oncol. 2008. PMID: 18802150 Clinical Trial.
Hypoxia modulates EWS-FLI1 transcriptional signature and enhances the malignant properties of Ewing's sarcoma cells in vitro.
Aryee DN, Niedan S, Kauer M, Schwentner R, Bennani-Baiti IM, Ban J, Muehlbacher K, Kreppel M, Walker RL, Meltzer P, Poremba C, Kofler R, Kovar H. Aryee DN, et al. Among authors: poremba c. Cancer Res. 2010 May 15;70(10):4015-23. doi: 10.1158/0008-5472.CAN-09-4333. Epub 2010 May 4. Cancer Res. 2010. PMID: 20442286 Free PMC article.
Microarray analysis of Ewing's sarcoma family of tumours reveals characteristic gene expression signatures associated with metastasis and resistance to chemotherapy.
Schaefer KL, Eisenacher M, Braun Y, Brachwitz K, Wai DH, Dirksen U, Lanvers-Kaminsky C, Juergens H, Herrero D, Stegmaier S, Koscielniak E, Eggert A, Nathrath M, Gosheger G, Schneider DT, Bury C, Diallo-Danebrock R, Ottaviano L, Gabbert HE, Poremba C. Schaefer KL, et al. Among authors: poremba c. Eur J Cancer. 2008 Mar;44(5):699-709. doi: 10.1016/j.ejca.2008.01.020. Epub 2008 Feb 21. Eur J Cancer. 2008. PMID: 18294840
189 results