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Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms.
Schefold JC, Zeden JP, Fotopoulou C, von Haehling S, Pschowski R, Hasper D, Volk HD, Schuett C, Reinke P. Schefold JC, et al. Among authors: reinke p. Nephrol Dial Transplant. 2009 Jun;24(6):1901-8. doi: 10.1093/ndt/gfn739. Epub 2009 Jan 20. Nephrol Dial Transplant. 2009. PMID: 19155537
Treatment with granulocyte-macrophage colony-stimulating factor is associated with reduced indoleamine 2,3-dioxygenase activity and kynurenine pathway catabolites in patients with severe sepsis and septic shock.
Schefold JC, Zeden JP, Pschowski R, Hammoud B, Fotopoulou C, Hasper D, Fusch G, Von Haehling S, Volk HD, Meisel C, Schütt C, Reinke P. Schefold JC, et al. Among authors: reinke p. Scand J Infect Dis. 2010 Mar;42(3):164-71. doi: 10.3109/00365540903405768. Scand J Infect Dis. 2010. PMID: 19958238 Clinical Trial.
Sepsis: time has come to focus on the later stages.
Schefold JC, Hasper D, Volk HD, Reinke P. Schefold JC, et al. Among authors: reinke p. Med Hypotheses. 2008 Aug;71(2):203-8. doi: 10.1016/j.mehy.2008.03.022. Epub 2008 Apr 29. Med Hypotheses. 2008. PMID: 18448264
Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial.
Meisel C, Schefold JC, Pschowski R, Baumann T, Hetzger K, Gregor J, Weber-Carstens S, Hasper D, Keh D, Zuckermann H, Reinke P, Volk HD. Meisel C, et al. Among authors: reinke p. Am J Respir Crit Care Med. 2009 Oct 1;180(7):640-8. doi: 10.1164/rccm.200903-0363OC. Epub 2009 Jul 9. Am J Respir Crit Care Med. 2009. PMID: 19590022 Clinical Trial.
Consider delayed immunosuppression into the concept of sepsis.
Schefold JC, Hasper D, Reinke P, Monneret G, Volk HD. Schefold JC, et al. Among authors: reinke p. Crit Care Med. 2008 Nov;36(11):3118. doi: 10.1097/CCM.0b013e31818bdd8f. Crit Care Med. 2008. PMID: 18941324 No abstract available.
409 results