Neel BG - Search Results

1

Impaired SHP2-mediated extracellular signal-regulated kinase activation contributes to gefitinib sensitivity of lung cancer cells with epidermal growth factor receptor-activating mutations.

Lazzara MJ, Lane K, Chan R, Jasper PJ, Yaffe MB, Sorger PK, Jacks T, Neel BG, Lauffenburger DA. Lazzara MJ, et al. Among authors: neel bg. Cancer Res. 2010 May 1;70(9):3843-50. doi: 10.1158/0008-5472.CAN-09-3421. Epub 2010 Apr 20. Cancer Res. 2010. PMID: 20406974 Free PMC article.

2

Receptor-specific regulation of phosphatidylinositol 3'-kinase activation by the protein tyrosine phosphatase Shp2.

Zhang SQ, Tsiaras WG, Araki T, Wen G, Minichiello L, Klein R, Neel BG. Zhang SQ, et al. Among authors: neel bg. Mol Cell Biol. 2002 Jun;22(12):4062-72. doi: 10.1128/MCB.22.12.4062-4072.2002. Mol Cell Biol. 2002. PMID: 12024020 Free PMC article.

3

Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatase-1B.

Haj FG, Markova B, Klaman LD, Bohmer FD, Neel BG. Haj FG, et al. Among authors: neel bg. J Biol Chem. 2003 Jan 10;278(2):739-44. doi: 10.1074/jbc.M210194200. Epub 2002 Nov 6. J Biol Chem. 2003. PMID: 12424235 Free article.

4

Increased expression of epidermal growth factor receptor induces sequestration of extracellular signal-related kinases and selective attenuation of specific epidermal growth factor-mediated signal transduction pathways.

Habib AA, Chun SJ, Neel BG, Vartanian T. Habib AA, et al. Among authors: neel bg. Mol Cancer Res. 2003 Jan;1(3):219-33. Mol Cancer Res. 2003. PMID: 12556561

5

Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia.

Bentires-Alj M, Paez JG, David FS, Keilhack H, Halmos B, Naoki K, Maris JM, Richardson A, Bardelli A, Sugarbaker DJ, Richards WG, Du J, Girard L, Minna JD, Loh ML, Fisher DE, Velculescu VE, Vogelstein B, Meyerson M, Sellers WR, Neel BG. Bentires-Alj M, et al. Among authors: neel bg. Cancer Res. 2004 Dec 15;64(24):8816-20. doi: 10.1158/0008-5472.CAN-04-1923. Cancer Res. 2004. PMID: 15604238

6

Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations.

Mohi MG, Williams IR, Dearolf CR, Chan G, Kutok JL, Cohen S, Morgan K, Boulton C, Shigematsu H, Keilhack H, Akashi K, Gilliland DG, Neel BG. Mohi MG, et al. Among authors: neel bg. Cancer Cell. 2005 Feb;7(2):179-91. doi: 10.1016/j.ccr.2005.01.010. Cancer Cell. 2005. PMID: 15710330 Free article.

7

A role for the scaffolding adapter GAB2 in breast cancer.

Bentires-Alj M, Gil SG, Chan R, Wang ZC, Wang Y, Imanaka N, Harris LN, Richardson A, Neel BG, Gu H. Bentires-Alj M, et al. Among authors: neel bg. Nat Med. 2006 Jan;12(1):114-21. doi: 10.1038/nm1341. Epub 2005 Dec 20. Nat Med. 2006. PMID: 16369543

8

PTPN11 (Shp2) mutations in LEOPARD syndrome have dominant negative, not activating, effects.

Kontaridis MI, Swanson KD, David FS, Barford D, Neel BG. Kontaridis MI, et al. Among authors: neel bg. J Biol Chem. 2006 Mar 10;281(10):6785-92. doi: 10.1074/jbc.M513068200. Epub 2005 Dec 23. J Biol Chem. 2006. PMID: 16377799 Free article.

9

Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer.

Bentires-Alj M, Neel BG. Bentires-Alj M, et al. Among authors: neel bg. Cancer Res. 2007 Mar 15;67(6):2420-4. doi: 10.1158/0008-5472.CAN-06-4610. Epub 2007 Mar 8. Cancer Res. 2007. PMID: 17347513

10

Control of CNS cell-fate decisions by SHP-2 and its dysregulation in Noonan syndrome.

Gauthier AS, Furstoss O, Araki T, Chan R, Neel BG, Kaplan DR, Miller FD. Gauthier AS, et al. Among authors: neel bg. Neuron. 2007 Apr 19;54(2):245-62. doi: 10.1016/j.neuron.2007.03.027. Neuron. 2007. PMID: 17442246 Free PMC article.

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