Sorger PK - Search Results

1

Impaired SHP2-mediated extracellular signal-regulated kinase activation contributes to gefitinib sensitivity of lung cancer cells with epidermal growth factor receptor-activating mutations.

Lazzara MJ, Lane K, Chan R, Jasper PJ, Yaffe MB, Sorger PK, Jacks T, Neel BG, Lauffenburger DA. Lazzara MJ, et al. Among authors: sorger pk. Cancer Res. 2010 May 1;70(9):3843-50. doi: 10.1158/0008-5472.CAN-09-3421. Epub 2010 Apr 20. Cancer Res. 2010. PMID: 20406974 Free PMC article.

2

Bayesian network approach to cell signaling pathway modeling.

Sachs K, Gifford D, Jaakkola T, Sorger P, Lauffenburger DA. Sachs K, et al. Sci STKE. 2002 Sep 3;2002(148):pe38. doi: 10.1126/stke.2002.148.pe38. Sci STKE. 2002. PMID: 12209052

3

A high-throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: application to sepsis-apoptosis.

Janes KA, Albeck JG, Peng LX, Sorger PK, Lauffenburger DA, Yaffe MB. Janes KA, et al. Among authors: sorger pk. Mol Cell Proteomics. 2003 Jul;2(7):463-73. doi: 10.1074/mcp.M300045-MCP200. Epub 2003 Jun 26. Mol Cell Proteomics. 2003. PMID: 12832460 Free article.

4

Profiling receptor tyrosine kinase activation by using Ab microarrays.

Nielsen UB, Cardone MH, Sinskey AJ, MacBeath G, Sorger PK. Nielsen UB, et al. Among authors: sorger pk. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9330-5. doi: 10.1073/pnas.1633513100. Epub 2003 Jul 22. Proc Natl Acad Sci U S A. 2003. PMID: 12876202 Free PMC article.

5

Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data.

Janes KA, Kelly JR, Gaudet S, Albeck JG, Sorger PK, Lauffenburger DA. Janes KA, et al. Among authors: sorger pk. J Comput Biol. 2004;11(4):544-61. doi: 10.1089/cmb.2004.11.544. J Comput Biol. 2004. PMID: 15579231

6

A compendium of signals and responses triggered by prodeath and prosurvival cytokines.

Gaudet S, Janes KA, Albeck JG, Pace EA, Lauffenburger DA, Sorger PK. Gaudet S, et al. Among authors: sorger pk. Mol Cell Proteomics. 2005 Oct;4(10):1569-90. doi: 10.1074/mcp.M500158-MCP200. Epub 2005 Jul 18. Mol Cell Proteomics. 2005. PMID: 16030008 Free article.

7

A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis.

Janes KA, Albeck JG, Gaudet S, Sorger PK, Lauffenburger DA, Yaffe MB. Janes KA, et al. Among authors: sorger pk. Science. 2005 Dec 9;310(5754):1646-53. doi: 10.1126/science.1116598. Science. 2005. PMID: 16339439

8

The response of human epithelial cells to TNF involves an inducible autocrine cascade.

Janes KA, Gaudet S, Albeck JG, Nielsen UB, Lauffenburger DA, Sorger PK. Janes KA, et al. Among authors: sorger pk. Cell. 2006 Mar 24;124(6):1225-39. doi: 10.1016/j.cell.2006.01.041. Cell. 2006. PMID: 16564013 Free article.

9

Collecting and organizing systematic sets of protein data.

Albeck JG, MacBeath G, White FM, Sorger PK, Lauffenburger DA, Gaudet S. Albeck JG, et al. Among authors: sorger pk. Nat Rev Mol Cell Biol. 2006 Nov;7(11):803-12. doi: 10.1038/nrm2042. Nat Rev Mol Cell Biol. 2006. PMID: 17057751 Review.

10

Physicochemical modelling of cell signalling pathways.

Aldridge BB, Burke JM, Lauffenburger DA, Sorger PK. Aldridge BB, et al. Among authors: sorger pk. Nat Cell Biol. 2006 Nov;8(11):1195-203. doi: 10.1038/ncb1497. Nat Cell Biol. 2006. PMID: 17060902 Review.

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