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Rapid and robust transgenic high-grade glioma mouse models for therapy intervention studies.
de Vries NA, Bruggeman SW, Hulsman D, de Vries HI, Zevenhoven J, Buckle T, Hamans BC, Leenders WP, Beijnen JH, van Lohuizen M, Berns AJ, van Tellingen O. de Vries NA, et al. Among authors: zevenhoven j. Clin Cancer Res. 2010 Jul 1;16(13):3431-41. doi: 10.1158/1078-0432.CCR-09-3414. Epub 2010 May 14. Clin Cancer Res. 2010. PMID: 20472681 Free article.
A conditional mouse model for malignant mesothelioma.
Jongsma J, van Montfort E, Vooijs M, Zevenhoven J, Krimpenfort P, van der Valk M, van de Vijver M, Berns A. Jongsma J, et al. Among authors: zevenhoven j. Cancer Cell. 2008 Mar;13(3):261-71. doi: 10.1016/j.ccr.2008.01.030. Cancer Cell. 2008. PMID: 18328429 Free article.
GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors.
Westerman BA, Blom M, Tanger E, van der Valk M, Song JY, van Santen M, Gadiot J, Cornelissen-Steijger P, Zevenhoven J, Prosser HM, Uren A, Aronica E, van Lohuizen M. Westerman BA, et al. Among authors: zevenhoven j. PLoS One. 2012;7(5):e35943. doi: 10.1371/journal.pone.0035943. Epub 2012 May 4. PLoS One. 2012. PMID: 22574128 Free PMC article.
Multiple cells-of-origin of mutant K-Ras-induced mouse lung adenocarcinoma.
Sutherland KD, Song JY, Kwon MC, Proost N, Zevenhoven J, Berns A. Sutherland KD, et al. Among authors: zevenhoven j. Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4952-7. doi: 10.1073/pnas.1319963111. Epub 2014 Feb 28. Proc Natl Acad Sci U S A. 2014. PMID: 24586047 Free PMC article.
Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.
Derksen PW, Liu X, Saridin F, van der Gulden H, Zevenhoven J, Evers B, van Beijnum JR, Griffioen AW, Vink J, Krimpenfort P, Peterse JL, Cardiff RD, Berns A, Jonkers J. Derksen PW, et al. Among authors: zevenhoven j. Cancer Cell. 2006 Nov;10(5):437-49. doi: 10.1016/j.ccr.2006.09.013. Cancer Cell. 2006. PMID: 17097565 Free article.
Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer.
Nacerddine K, Beaudry JB, Ginjala V, Westerman B, Mattiroli F, Song JY, van der Poel H, Ponz OB, Pritchard C, Cornelissen-Steijger P, Zevenhoven J, Tanger E, Sixma TK, Ganesan S, van Lohuizen M. Nacerddine K, et al. Among authors: zevenhoven j. J Clin Invest. 2012 May;122(5):1920-32. doi: 10.1172/JCI57477. Epub 2012 Apr 16. J Clin Invest. 2012. PMID: 22505453 Free PMC article.
Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice.
Badhai J, Pandey GK, Song JY, Krijgsman O, Bhaskaran R, Chandrasekaran G, Kwon MC, Bombardelli L, Monkhorst K, Grasso C, Zevenhoven J, van der Vliet J, Cozijnsen M, Krimpenfort P, Peeper D, van Lohuizen M, Berns A. Badhai J, et al. Among authors: zevenhoven j. J Exp Med. 2020 Jun 1;217(6):e20191257. doi: 10.1084/jem.20191257. J Exp Med. 2020. PMID: 32271879 Free PMC article.
24 results