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159 results

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Page 1
Loss of naive T cells and repertoire constriction predict poor response to vaccination in old primates.
Cicin-Sain L, Smyk-Pearson S, Currier N, Byrd L, Koudelka C, Robinson T, Swarbrick G, Tackitt S, Legasse A, Fischer M, Nikolich-Zugich D, Park B, Hobbs T, Doane CJ, Mori M, Axthelm MK, Lewinsohn DA, Nikolich-Zugich J. Cicin-Sain L, et al. Among authors: axthelm mk. J Immunol. 2010 Jun 15;184(12):6739-45. doi: 10.4049/jimmunol.0904193. Epub 2010 May 17. J Immunol. 2010. PMID: 20483749 Free PMC article.
Development and homeostasis of T cell memory in rhesus macaque.
Pitcher CJ, Hagen SI, Walker JM, Lum R, Mitchell BL, Maino VC, Axthelm MK, Picker LJ. Pitcher CJ, et al. Among authors: axthelm mk. J Immunol. 2002 Jan 1;168(1):29-43. doi: 10.4049/jimmunol.168.1.29. J Immunol. 2002. PMID: 11751943
Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection.
Okoye A, Meier-Schellersheim M, Brenchley JM, Hagen SI, Walker JM, Rohankhedkar M, Lum R, Edgar JB, Planer SL, Legasse A, Sylwester AW, Piatak M Jr, Lifson JD, Maino VC, Sodora DL, Douek DC, Axthelm MK, Grossman Z, Picker LJ. Okoye A, et al. Among authors: axthelm mk. J Exp Med. 2007 Sep 3;204(9):2171-85. doi: 10.1084/jem.20070567. Epub 2007 Aug 27. J Exp Med. 2007. PMID: 17724130 Free PMC article.
Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates.
Cicin-Sain L, Messaoudi I, Park B, Currier N, Planer S, Fischer M, Tackitt S, Nikolich-Zugich D, Legasse A, Axthelm MK, Picker LJ, Mori M, Nikolich-Zugich J. Cicin-Sain L, et al. Among authors: axthelm mk. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19960-5. doi: 10.1073/pnas.0705905104. Epub 2007 Dec 4. Proc Natl Acad Sci U S A. 2007. PMID: 18056811 Free PMC article.
Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge.
Hansen SG, Vieville C, Whizin N, Coyne-Johnson L, Siess DC, Drummond DD, Legasse AW, Axthelm MK, Oswald K, Trubey CM, Piatak M Jr, Lifson JD, Nelson JA, Jarvis MA, Picker LJ. Hansen SG, et al. Among authors: axthelm mk. Nat Med. 2009 Mar;15(3):293-9. doi: 10.1038/nm.1935. Epub 2009 Feb 15. Nat Med. 2009. PMID: 19219024 Free PMC article.
Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis.
Okoye A, Park H, Rohankhedkar M, Coyne-Johnson L, Lum R, Walker JM, Planer SL, Legasse AW, Sylwester AW, Piatak M Jr, Lifson JD, Sodora DL, Villinger F, Axthelm MK, Schmitz JE, Picker LJ. Okoye A, et al. Among authors: axthelm mk. J Exp Med. 2009 Jul 6;206(7):1575-88. doi: 10.1084/jem.20090356. Epub 2009 Jun 22. J Exp Med. 2009. PMID: 19546246 Free PMC article.
Evasion of CD8+ T cells is critical for superinfection by cytomegalovirus.
Hansen SG, Powers CJ, Richards R, Ventura AB, Ford JC, Siess D, Axthelm MK, Nelson JA, Jarvis MA, Picker LJ, Früh K. Hansen SG, et al. Among authors: axthelm mk. Science. 2010 Apr 2;328(5974):102-6. doi: 10.1126/science.1185350. Science. 2010. PMID: 20360110 Free PMC article.
Increased CD4+ T cell levels during IL-7 administration of antiretroviral therapy-treated simian immunodeficiency virus-positive macaques are not dependent on strong proliferative responses.
Leone A, Rohankhedkar M, Okoye A, Legasse A, Axthelm MK, Villinger F, Piatak M Jr, Lifson JD, Assouline B, Morre M, Picker LJ, Sodora DL. Leone A, et al. Among authors: axthelm mk. J Immunol. 2010 Aug 1;185(3):1650-9. doi: 10.4049/jimmunol.0902626. Epub 2010 Jul 9. J Immunol. 2010. PMID: 20622118 Free PMC article.
Immune response to the West Nile virus in aged non-human primates.
Wertheimer AM, Uhrlaub JL, Hirsch A, Medigeshi G, Sprague J, Legasse A, Wilk J, Wiley CA, Didier P, Tesh RB, Murray KO, Axthelm MK, Wong SW, Nikolich-Žugich J. Wertheimer AM, et al. Among authors: axthelm mk. PLoS One. 2010 Dec 2;5(12):e15514. doi: 10.1371/journal.pone.0015514. PLoS One. 2010. PMID: 21151986 Free PMC article.
159 results