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Metabolic changes in type 2 diabetes are reflected in peripheral blood cells, revealing aberrant cytotoxicity, a viral signature, and hypoxia inducible factor activity.
van der Pouw Kraan TC, Chen WJ, Bunck MC, van Raalte DH, van der Zijl NJ, van Genugten RE, van Bloemendaal L, Baggen JM, Serné EH, Diamant M, Horrevoets AJ. van der Pouw Kraan TC, et al. Among authors: horrevoets aj. BMC Med Genomics. 2015 May 9;8:20. doi: 10.1186/s12920-015-0096-y. BMC Med Genomics. 2015. PMID: 25956355 Free PMC article.
Thiopurine treatment in patients with Crohn's disease leads to a selective reduction of an effector cytotoxic gene expression signature revealed by whole-genome expression profiling.
Bouma G, Baggen JM, van Bodegraven AA, Mulder CJ, Kraal G, Zwiers A, Horrevoets AJ, van der Pouw Kraan CT. Bouma G, et al. Among authors: horrevoets aj. Mol Immunol. 2013 Jul;54(3-4):472-81. doi: 10.1016/j.molimm.2013.01.015. Epub 2013 Feb 27. Mol Immunol. 2013. PMID: 23454163
Galectin-2 expression is dependent on the rs7291467 polymorphism and acts as an inhibitor of arteriogenesis.
van der Laan AM, Schirmer SH, de Vries MR, Koning JJ, Volger OL, Fledderus JO, Bastiaansen AJ, Hollander MR, Baggen JM, Koch KT, Baan J Jr, Henriques JP, van der Schaaf RJ, Vis MM, Mebius RE, van der Pouw Kraan TC, Quax PH, Piek JJ, Horrevoets AJ, van Royen N. van der Laan AM, et al. Among authors: horrevoets aj. Eur Heart J. 2012 May;33(9):1076-84. doi: 10.1093/eurheartj/ehr220. Epub 2011 Aug 10. Eur Heart J. 2012. PMID: 21831908
CD40 in coronary artery disease: a matter of macrophages?
Jansen MF, Hollander MR, van Royen N, Horrevoets AJ, Lutgens E. Jansen MF, et al. Among authors: horrevoets aj. Basic Res Cardiol. 2016 Jul;111(4):38. doi: 10.1007/s00395-016-0554-5. Epub 2016 May 4. Basic Res Cardiol. 2016. PMID: 27146510 Free PMC article. Review.
Interferon-beta signaling is enhanced in patients with insufficient coronary collateral artery development and inhibits arteriogenesis in mice.
Schirmer SH, Fledderus JO, Bot PT, Moerland PD, Hoefer IE, Baan J Jr, Henriques JP, van der Schaaf RJ, Vis MM, Horrevoets AJ, Piek JJ, van Royen N. Schirmer SH, et al. Among authors: horrevoets aj. Circ Res. 2008 May 23;102(10):1286-94. doi: 10.1161/CIRCRESAHA.108.171827. Epub 2008 Apr 17. Circ Res. 2008. PMID: 18420941
109 results