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Generation and therapeutic efficacy of highly oligomer-specific beta-amyloid antibodies.
Hillen H, Barghorn S, Striebinger A, Labkovsky B, Müller R, Nimmrich V, Nolte MW, Perez-Cruz C, van der Auwera I, van Leuven F, van Gaalen M, Bespalov AY, Schoemaker H, Sullivan JP, Ebert U. Hillen H, et al. Among authors: van leuven f, van der auwera i, van gaalen m. J Neurosci. 2010 Aug 4;30(31):10369-79. doi: 10.1523/JNEUROSCI.5721-09.2010. J Neurosci. 2010. PMID: 20685980 Free PMC article.
Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice.
Muhs A, Hickman DT, Pihlgren M, Chuard N, Giriens V, Meerschman C, van der Auwera I, van Leuven F, Sugawara M, Weingertner MC, Bechinger B, Greferath R, Kolonko N, Nagel-Steger L, Riesner D, Brady RO, Pfeifer A, Nicolau C. Muhs A, et al. Among authors: van leuven f, van der auwera i. Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9810-5. doi: 10.1073/pnas.0703137104. Epub 2007 May 21. Proc Natl Acad Sci U S A. 2007. PMID: 17517595 Free PMC article.
Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice.
Etcheberrigaray R, Tan M, Dewachter I, Kuipéri C, Van der Auwera I, Wera S, Qiao L, Bank B, Nelson TJ, Kozikowski AP, Van Leuven F, Alkon DL. Etcheberrigaray R, et al. Among authors: van leuven f, van der auwera i. Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):11141-6. doi: 10.1073/pnas.0403921101. Epub 2004 Jul 19. Proc Natl Acad Sci U S A. 2004. PMID: 15263077 Free PMC article.
Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.
Dewachter I, Reversé D, Caluwaerts N, Ris L, Kuipéri C, Van den Haute C, Spittaels K, Umans L, Serneels L, Thiry E, Moechars D, Mercken M, Godaux E, Van Leuven F. Dewachter I, et al. Among authors: van leuven f, van den haute c. J Neurosci. 2002 May 1;22(9):3445-53. doi: 10.1523/JNEUROSCI.22-09-03445.2002. J Neurosci. 2002. PMID: 11978821 Free PMC article.
Neuronal or glial expression of human apolipoprotein e4 affects parenchymal and vascular amyloid pathology differentially in different brain regions of double- and triple-transgenic mice.
Van Dooren T, Muyllaert D, Borghgraef P, Cresens A, Devijver H, Van der Auwera I, Wera S, Dewachter I, Van Leuven F. Van Dooren T, et al. Among authors: van leuven f, van der auwera i. Am J Pathol. 2006 Jan;168(1):245-60. doi: 10.2353/ajpath.2006.050752. Am J Pathol. 2006. PMID: 16400027 Free PMC article.
Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase.
Sastre M, Dewachter I, Landreth GE, Willson TM, Klockgether T, van Leuven F, Heneka MT. Sastre M, et al. Among authors: van leuven f. J Neurosci. 2003 Oct 29;23(30):9796-804. doi: 10.1523/JNEUROSCI.23-30-09796.2003. J Neurosci. 2003. PMID: 14586007 Free PMC article.
Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
Tamboli IY, Prager K, Thal DR, Thelen KM, Dewachter I, Pietrzik CU, St George-Hyslop P, Sisodia SS, De Strooper B, Heneka MT, Filippov MA, Müller U, van Leuven F, Lütjohann D, Walter J. Tamboli IY, et al. Among authors: van leuven f. J Neurosci. 2008 Nov 12;28(46):12097-106. doi: 10.1523/JNEUROSCI.2635-08.2008. J Neurosci. 2008. PMID: 19005074 Free PMC article.
340 results