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High-throughput screening and selection of yeast cell lines expressing monoclonal antibodies.
Barnard GC, Kull AR, Sharkey NS, Shaikh SS, Rittenhour AM, Burnina I, Jiang Y, Li F, Lynaugh H, Mitchell T, Nett JH, Nylen A, Potgieter TI, Prinz B, Rios SE, Zha D, Sethuraman N, Stadheim TA, Bobrowicz P. Barnard GC, et al. Among authors: mitchell t. J Ind Microbiol Biotechnol. 2010 Sep;37(9):961-71. doi: 10.1007/s10295-010-0746-1. Epub 2010 Aug 15. J Ind Microbiol Biotechnol. 2010. PMID: 20711797
Production of monoclonal antibodies by glycoengineered Pichia pastoris.
Potgieter TI, Cukan M, Drummond JE, Houston-Cummings NR, Jiang Y, Li F, Lynaugh H, Mallem M, McKelvey TW, Mitchell T, Nylen A, Rittenhour A, Stadheim TA, Zha D, d'Anjou M. Potgieter TI, et al. Among authors: mitchell t. J Biotechnol. 2009 Feb 23;139(4):318-25. doi: 10.1016/j.jbiotec.2008.12.015. Epub 2008 Dec 27. J Biotechnol. 2009. PMID: 19162096
Production of complex human glycoproteins in yeast.
Hamilton SR, Bobrowicz P, Bobrowicz B, Davidson RC, Li H, Mitchell T, Nett JH, Rausch S, Stadheim TA, Wischnewski H, Wildt S, Gerngross TU. Hamilton SR, et al. Among authors: mitchell t. Science. 2003 Aug 29;301(5637):1244-6. doi: 10.1126/science.1088166. Science. 2003. PMID: 12947202
Engineering of an artificial glycosylation pathway blocked in core oligosaccharide assembly in the yeast Pichia pastoris: production of complex humanized glycoproteins with terminal galactose.
Bobrowicz P, Davidson RC, Li H, Potgieter TI, Nett JH, Hamilton SR, Stadheim TA, Miele RG, Bobrowicz B, Mitchell T, Rausch S, Renfer E, Wildt S. Bobrowicz P, et al. Among authors: mitchell t. Glycobiology. 2004 Sep;14(9):757-66. doi: 10.1093/glycob/cwh104. Epub 2004 Jun 9. Glycobiology. 2004. PMID: 15190003
Humanization of yeast to produce complex terminally sialylated glycoproteins.
Hamilton SR, Davidson RC, Sethuraman N, Nett JH, Jiang Y, Rios S, Bobrowicz P, Stadheim TA, Li H, Choi BK, Hopkins D, Wischnewski H, Roser J, Mitchell T, Strawbridge RR, Hoopes J, Wildt S, Gerngross TU. Hamilton SR, et al. Among authors: mitchell t. Science. 2006 Sep 8;313(5792):1441-3. doi: 10.1126/science.1130256. Science. 2006. PMID: 16960007
Elimination of β-mannose glycan structures in Pichia pastoris.
Hopkins D, Gomathinayagam S, Rittenhour AM, Du M, Hoyt E, Karaveg K, Mitchell T, Nett JH, Sharkey NJ, Stadheim TA, Li H, Hamilton SR. Hopkins D, et al. Among authors: mitchell t. Glycobiology. 2011 Dec;21(12):1616-26. doi: 10.1093/glycob/cwr108. Epub 2011 Aug 12. Glycobiology. 2011. PMID: 21840970
Optimization of erythropoietin production with controlled glycosylation-PEGylated erythropoietin produced in glycoengineered Pichia pastoris.
Nett JH, Gomathinayagam S, Hamilton SR, Gong B, Davidson RC, Du M, Hopkins D, Mitchell T, Mallem MR, Nylen A, Shaikh SS, Sharkey N, Barnard GC, Copeland V, Liu L, Evers R, Li Y, Gray PM, Lingham RB, Visco D, Forrest G, DeMartino J, Linden T, Potgieter TI, Wildt S, Stadheim TA, d'Anjou M, Li H, Sethuraman N. Nett JH, et al. Among authors: mitchell t. J Biotechnol. 2012 Jan;157(1):198-206. doi: 10.1016/j.jbiotec.2011.11.002. Epub 2011 Nov 9. J Biotechnol. 2012. PMID: 22100268
2,041 results