Patel HJ - Search Results

1

Blockade of endothelin-1 with a novel series of 1,3,6-trisubstituted-2-carboxy-quinol-4-ones controls infection-associated preterm birth.

Olgun NS, Patel HJ, Stephani R, Lengyel I, Reznik SE. Olgun NS, et al. Among authors: patel hj. Am J Pathol. 2010 Oct;177(4):1929-35. doi: 10.2353/ajpath.2010.100281. Epub 2010 Aug 27. Am J Pathol. 2010. PMID: 20802183 Free PMC article.

2

Effect of the putative novel selective ETA-receptor antagonist HJP272, a 1,3,6-trisubstituted-2-carboxy-quinol-4-one, on infection-mediated premature delivery.

Olgun N, Patel HJ, Stephani R, Wang W, Yen H, Reznik SE. Olgun N, et al. Among authors: patel hj. Can J Physiol Pharmacol. 2008 Aug;86(8):571-5. doi: 10.1139/Y08-057. Can J Physiol Pharmacol. 2008. PMID: 18758506 Free article.

3

Synthesis and pharmacological activity of 1,3,6-trisubstituted-4-oxo-1,4-dihydroquinoline-2-carboxylic acids as selective ET(A) antagonists.

Patel HJ, Olgun N, Lengyel I, Reznik S, Stephani RA. Patel HJ, et al. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6840-4. doi: 10.1016/j.bmcl.2010.08.074. Bioorg Med Chem Lett. 2010. PMID: 20932745

4

Preferential recruitment of neutrophils by endothelin-1 in acute lung inflammation induced by lipopolysaccharide or cigarette smoke.

Bhavsar T, Liu XJ, Patel H, Stephani R, Cantor JO. Bhavsar T, et al. Int J Chron Obstruct Pulmon Dis. 2008;3(3):477-81. doi: 10.2147/copd.s2837. Int J Chron Obstruct Pulmon Dis. 2008. PMID: 18990977 Free PMC article.

5

HJP272, a novel endothelin receptor antagonist, attenuates lipopolysaccharide-induced acute lung injury in hamsters.

Patel S, Liu X, Liu M, Stephani R, Patel H, Cantor J. Patel S, et al. Lung. 2014 Oct;192(5):803-10. doi: 10.1007/s00408-014-9628-z. Epub 2014 Aug 3. Lung. 2014. PMID: 25087133

6

Synthesis and anticonvulsant activity of new N-1',N-3'-disubstituted-2'H,3H,5'H-spiro-(2-benzofuran-1,4'-imidazolidine)-2',3,5'-triones.

Patel HJ, Sarra J, Caruso F, Rossi M, Doshi U, Stephani RA. Patel HJ, et al. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4644-7. doi: 10.1016/j.bmcl.2006.05.102. Epub 2006 Jun 21. Bioorg Med Chem Lett. 2006. PMID: 16793262

7

Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2.

Patel PD, Yan P, Seidler PM, Patel HJ, Sun W, Yang C, Que NS, Taldone T, Finotti P, Stephani RA, Gewirth DT, Chiosis G. Patel PD, et al. Among authors: patel hj. Nat Chem Biol. 2013 Nov;9(11):677-84. doi: 10.1038/nchembio.1335. Epub 2013 Sep 1. Nat Chem Biol. 2013. PMID: 23995768 Free PMC article.

8

Structure-activity relationship in a purine-scaffold compound series with selectivity for the endoplasmic reticulum Hsp90 paralog Grp94.

Patel HJ, Patel PD, Ochiana SO, Yan P, Sun W, Patel MR, Shah SK, Tramentozzi E, Brooks J, Bolaender A, Shrestha L, Stephani R, Finotti P, Leifer C, Li Z, Gewirth DT, Taldone T, Chiosis G. Patel HJ, et al. Among authors: patel mr, patel pd. J Med Chem. 2015 May 14;58(9):3922-43. doi: 10.1021/acs.jmedchem.5b00197. Epub 2015 Apr 22. J Med Chem. 2015. PMID: 25901531 Free PMC article.

9

Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein.

Rodina A, Patel PD, Kang Y, Patel Y, Baaklini I, Wong MJ, Taldone T, Yan P, Yang C, Maharaj R, Gozman A, Patel MR, Patel HJ, Chirico W, Erdjument-Bromage H, Talele TT, Young JC, Chiosis G. Rodina A, et al. Among authors: patel y, patel mr, patel pd, patel hj. Chem Biol. 2013 Dec 19;20(12):1469-80. doi: 10.1016/j.chembiol.2013.10.008. Epub 2013 Nov 14. Chem Biol. 2013. PMID: 24239008 Free PMC article.

10

Heat Shock Protein (HSP) Drug Discovery and Development: Targeting Heat Shock Proteins in Disease.

Shrestha L, Bolaender A, Patel HJ, Taldone T. Shrestha L, et al. Among authors: patel hj. Curr Top Med Chem. 2016;16(25):2753-64. doi: 10.2174/1568026616666160413141911. Curr Top Med Chem. 2016. PMID: 27072696 Free PMC article. Review.

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