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Characterization of a cannabinoid CB2 receptor-selective agonist, A-836339 [2,2,3,3-tetramethyl-cyclopropanecarboxylic acid [3-(2-methoxy-ethyl)-4,5-dimethyl-3H-thiazol-(2Z)-ylidene]-amide], using in vitro pharmacological assays, in vivo pain models, and pharmacological magnetic resonance imaging.
Yao BB, Hsieh G, Daza AV, Fan Y, Grayson GK, Garrison TR, El Kouhen O, Hooker BA, Pai M, Wensink EJ, Salyers AK, Chandran P, Zhu CZ, Zhong C, Ryther K, Gallagher ME, Chin CL, Tovcimak AE, Hradil VP, Fox GB, Dart MJ, Honore P, Meyer MD. Yao BB, et al. Among authors: fox gb. J Pharmacol Exp Ther. 2009 Jan;328(1):141-51. doi: 10.1124/jpet.108.145011. Epub 2008 Oct 17. J Pharmacol Exp Ther. 2009. PMID: 18931146
Awake rat pharmacological magnetic resonance imaging as a translational pharmacodynamic biomarker: metabotropic glutamate 2/3 agonist modulation of ketamine-induced blood oxygenation level dependence signals.
Chin CL, Upadhyay J, Marek GJ, Baker SJ, Zhang M, Mezler M, Fox GB, Day M. Chin CL, et al. Among authors: fox gb. J Pharmacol Exp Ther. 2011 Mar;336(3):709-15. doi: 10.1124/jpet.110.173880. Epub 2010 Dec 20. J Pharmacol Exp Ther. 2011. PMID: 21172908
Paradigm shift in translational neuroimaging of CNS disorders.
Sakoğlu U, Upadhyay J, Chin CL, Chandran P, Baker SJ, Cole TB, Fox GB, Day M, Luo F. Sakoğlu U, et al. Among authors: fox gb. Biochem Pharmacol. 2011 Jun 15;81(12):1374-87. doi: 10.1016/j.bcp.2010.12.029. Epub 2011 Jan 8. Biochem Pharmacol. 2011. PMID: 21219879 Review.
105 results