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HIV-1 Gag p17 presented as virus-like particles on the E2 scaffold from Geobacillus stearothermophilus induces sustained humoral and cellular immune responses in the absence of IFNγ production by CD4+ T cells.
Caivano A, Doria-Rose NA, Buelow B, Sartorius R, Trovato M, D'Apice L, Domingo GJ, Sutton WF, Haigwood NL, De Berardinis P. Caivano A, et al. Among authors: trovato m. Virology. 2010 Nov 25;407(2):296-305. doi: 10.1016/j.virol.2010.08.026. Epub 2010 Sep 20. Virology. 2010. PMID: 20850858 Free PMC article.
Vaccination with filamentous bacteriophages targeting DEC-205 induces DC maturation and potent anti-tumor T-cell responses in the absence of adjuvants.
Sartorius R, Bettua C, D'Apice L, Caivano A, Trovato M, Russo D, Zanoni I, Granucci F, Mascolo D, Barba P, Del Pozzo G, De Berardinis P. Sartorius R, et al. Among authors: trovato m. Eur J Immunol. 2011 Sep;41(9):2573-84. doi: 10.1002/eji.201141526. Epub 2011 Aug 18. Eur J Immunol. 2011. PMID: 21688262 Free article.
Co-immunization with multimeric scaffolds and DNA rapidly induces potent autologous HIV-1 neutralizing antibodies and CD8+ T cells.
Jaworski JP, Krebs SJ, Trovato M, Kovarik DN, Brower Z, Sutton WF, Waagmeester G, Sartorius R, D'Apice L, Caivano A, Doria-Rose NA, Malherbe D, Montefiori DC, Barnett S, De Berardinis P, Haigwood NL. Jaworski JP, et al. Among authors: trovato m. PLoS One. 2012;7(2):e31464. doi: 10.1371/journal.pone.0031464. Epub 2012 Feb 16. PLoS One. 2012. PMID: 22359593 Free PMC article.
Design and characterization of a peptide mimotope of the HIV-1 gp120 bridging sheet.
Schiavone M, Fiume G, Caivano A, De Laurentiis A, Falcone C, Masci FF, Iaccino E, Mimmi S, Palmieri C, Pisano A, Pontoriero M, Rossi A, Scialdone A, Vecchio E, Andreozzi C, Trovato M, Rafay J, Ferko B, Montefiori D, Lombardi A, Morsica G, Poli G, Quinto I, Pavone V, De Berardinis P, Scala G. Schiavone M, et al. Among authors: trovato m. Int J Mol Sci. 2012;13(5):5674-5699. doi: 10.3390/ijms13055674. Epub 2012 May 10. Int J Mol Sci. 2012. PMID: 22754323 Free PMC article.
Delivery strategies for novel vaccine formulations.
Trovato M, Krebs SJ, Haigwood NL, De Berardinis P. Trovato M, et al. World J Virol. 2012 Feb 12;1(1):4-10. doi: 10.5501/wjv.v1.i1.4. World J Virol. 2012. PMID: 24175206 Free PMC article.
Multimeric scaffolds displaying the HIV-1 envelope MPER induce MPER-specific antibodies and cross-neutralizing antibodies when co-immunized with gp160 DNA.
Krebs SJ, McBurney SP, Kovarik DN, Waddell CD, Jaworski JP, Sutton WF, Gomes MM, Trovato M, Waagmeester G, Barnett SJ, DeBerardinis P, Haigwood NL. Krebs SJ, et al. Among authors: trovato m. PLoS One. 2014 Dec 16;9(12):e113463. doi: 10.1371/journal.pone.0113463. eCollection 2014. PLoS One. 2014. PMID: 25514675 Free PMC article.
Antigen delivery by filamentous bacteriophage fd displaying an anti-DEC-205 single-chain variable fragment confers adjuvanticity by triggering a TLR9-mediated immune response.
Sartorius R, D'Apice L, Trovato M, Cuccaro F, Costa V, De Leo MG, Marzullo VM, Biondo C, D'Auria S, De Matteis MA, Ciccodicola A, De Berardinis P. Sartorius R, et al. Among authors: trovato m. EMBO Mol Med. 2015 Apr 17;7(7):973-88. doi: 10.15252/emmm.201404525. Print 2015 Jul. EMBO Mol Med. 2015. PMID: 25888235 Free PMC article.
Novel antigen delivery systems.
Trovato M, De Berardinis P. Trovato M, et al. World J Virol. 2015 Aug 12;4(3):156-68. doi: 10.5501/wjv.v4.i3.156. World J Virol. 2015. PMID: 26279977 Free PMC article.
424 results