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Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species.
Kraaij MD, Savage ND, van der Kooij SW, Koekkoek K, Wang J, van den Berg JM, Ottenhoff TH, Kuijpers TW, Holmdahl R, van Kooten C, Gelderman KA. Kraaij MD, et al. Among authors: ottenhoff th. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17686-91. doi: 10.1073/pnas.1012016107. Epub 2010 Sep 22. Proc Natl Acad Sci U S A. 2010. PMID: 20861446 Free PMC article.
Definition of a human suppressor T-cell epitope.
Mutis T, Cornelisse YE, Datema G, van den Elsen PJ, Ottenhoff TH, de Vries RR. Mutis T, et al. Among authors: ottenhoff th. Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9456-60. doi: 10.1073/pnas.91.20.9456. Proc Natl Acad Sci U S A. 1994. PMID: 7524076 Free PMC article.
Interference with T cell receptor-HLA-DR interactions by Epstein-Barr virus gp42 results in reduced T helper cell recognition.
Ressing ME, van Leeuwen D, Verreck FA, Gomez R, Heemskerk B, Toebes M, Mullen MM, Jardetzky TS, Longnecker R, Schilham MW, Ottenhoff TH, Neefjes J, Schumacher TN, Hutt-Fletcher LM, Wiertz EJ. Ressing ME, et al. Among authors: ottenhoff th. Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11583-8. doi: 10.1073/pnas.2034960100. Epub 2003 Sep 22. Proc Natl Acad Sci U S A. 2003. PMID: 14504389 Free PMC article.
Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria.
Verreck FA, de Boer T, Langenberg DM, Hoeve MA, Kramer M, Vaisberg E, Kastelein R, Kolk A, de Waal-Malefyt R, Ottenhoff TH. Verreck FA, et al. Among authors: ottenhoff th. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4560-5. doi: 10.1073/pnas.0400983101. Epub 2004 Mar 19. Proc Natl Acad Sci U S A. 2004. PMID: 15070757 Free PMC article.
Identification of a human CD8+ regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4.
Joosten SA, van Meijgaarden KE, Savage ND, de Boer T, Triebel F, van der Wal A, de Heer E, Klein MR, Geluk A, Ottenhoff TH. Joosten SA, et al. Among authors: ottenhoff th. Proc Natl Acad Sci U S A. 2007 May 8;104(19):8029-34. doi: 10.1073/pnas.0702257104. Epub 2007 May 2. Proc Natl Acad Sci U S A. 2007. PMID: 17483450 Free PMC article.
Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1.
Kuijl C, Savage ND, Marsman M, Tuin AW, Janssen L, Egan DA, Ketema M, van den Nieuwendijk R, van den Eeden SJ, Geluk A, Poot A, van der Marel G, Beijersbergen RL, Overkleeft H, Ottenhoff TH, Neefjes J. Kuijl C, et al. Among authors: ottenhoff th. Nature. 2007 Nov 29;450(7170):725-30. doi: 10.1038/nature06345. Nature. 2007. PMID: 18046412
Influenza virus vaccination induces interleukin-12/23 receptor beta 1 (IL-12/23R beta 1)-independent production of gamma interferon (IFN-gamma) and humoral immunity in patients with genetic deficiencies in IL-12/23R beta 1 or IFN-gamma receptor I.
de Boer T, van Dissel JT, Kuijpers TW, Rimmelzwaan GF, Kroon FP, Ottenhoff TH. de Boer T, et al. Among authors: ottenhoff th. Clin Vaccine Immunol. 2008 Aug;15(8):1171-5. doi: 10.1128/CVI.00090-08. Epub 2008 Jun 18. Clin Vaccine Immunol. 2008. PMID: 18562567 Free PMC article.
514 results