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Azaindole N-methyl hydroxamic acids as HIV-1 integrase inhibitors-II. The impact of physicochemical properties on ADME and PK.
Tanis SP, Plewe MB, Johnson TW, Butler SL, Dalvie D, DeLisle D, Dress KR, Hu Q, Huang B, Kuehler JE, Kuki A, Liu W, Peng Q, Smith GL, Solowiej J, Tran KT, Wang H, Yang A, Yin C, Yu X, Zhang J, Zhu H. Tanis SP, et al. Among authors: yu x. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7429-34. doi: 10.1016/j.bmcl.2010.10.022. Epub 2010 Oct 13. Bioorg Med Chem Lett. 2010. PMID: 21036042
Design and synthesis of novel N-hydroxy-dihydronaphthyridinones as potent and orally bioavailable HIV-1 integrase inhibitors.
Johnson TW, Tanis SP, Butler SL, Dalvie D, Delisle DM, Dress KR, Flahive EJ, Hu Q, Kuehler JE, Kuki A, Liu W, McClellan GA, Peng Q, Plewe MB, Richardson PF, Smith GL, Solowiej J, Tran KT, Wang H, Yu X, Zhang J, Zhu H. Johnson TW, et al. Among authors: yu x. J Med Chem. 2011 May 12;54(9):3393-417. doi: 10.1021/jm200208d. Epub 2011 Apr 13. J Med Chem. 2011. PMID: 21446745
A non-toxic Hsp90 inhibitor protects neurons from Abeta-induced toxicity.
Ansar S, Burlison JA, Hadden MK, Yu XM, Desino KE, Bean J, Neckers L, Audus KL, Michaelis ML, Blagg BS. Ansar S, et al. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1984-90. doi: 10.1016/j.bmcl.2007.01.017. Epub 2007 Jan 17. Bioorg Med Chem Lett. 2007. PMID: 17276679
Syntheses of photolabile novobiocin analogues.
Shen G, Yu XM, Blagg BS. Shen G, et al. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5903-6. doi: 10.1016/j.bmcl.2004.09.017. Bioorg Med Chem Lett. 2004. PMID: 15501066
32,154 results
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