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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation.
Nazarian R, Shi H, Wang Q, Kong X, Koya RC, Lee H, Chen Z, Lee MK, Attar N, Sazegar H, Chodon T, Nelson SF, McArthur G, Sosman JA, Ribas A, Lo RS. Nazarian R, et al. Among authors: attar n. Nature. 2010 Dec 16;468(7326):973-7. doi: 10.1038/nature09626. Epub 2010 Nov 24. Nature. 2010. PMID: 21107323 Free PMC article.
Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032.
Søndergaard JN, Nazarian R, Wang Q, Guo D, Hsueh T, Mok S, Sazegar H, MacConaill LE, Barretina JG, Kehoe SM, Attar N, von Euw E, Zuckerman JE, Chmielowski B, Comin-Anduix B, Koya RC, Mischel PS, Lo RS, Ribas A. Søndergaard JN, et al. Among authors: attar n. J Transl Med. 2010 Apr 20;8:39. doi: 10.1186/1479-5876-8-39. J Transl Med. 2010. PMID: 20406486 Free PMC article.
Endoplasmic reticulum-mitochondria junction is required for iron homeostasis.
Xue Y, Schmollinger S, Attar N, Campos OA, Vogelauer M, Carey MF, Merchant SS, Kurdistani SK. Xue Y, et al. Among authors: attar n. J Biol Chem. 2017 Aug 11;292(32):13197-13204. doi: 10.1074/jbc.M117.784249. Epub 2017 Jun 21. J Biol Chem. 2017. PMID: 28637866 Free PMC article.
The histone H3-H4 tetramer is a copper reductase enzyme.
Attar N, Campos OA, Vogelauer M, Cheng C, Xue Y, Schmollinger S, Salwinski L, Mallipeddi NV, Boone BA, Yen L, Yang S, Zikovich S, Dardine J, Carey MF, Merchant SS, Kurdistani SK. Attar N, et al. Science. 2020 Jul 3;369(6499):59-64. doi: 10.1126/science.aba8740. Science. 2020. PMID: 32631887 Free PMC article.
301 results