Chodon T - Search Results

1

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation.

Nazarian R, Shi H, Wang Q, Kong X, Koya RC, Lee H, Chen Z, Lee MK, Attar N, Sazegar H, Chodon T, Nelson SF, McArthur G, Sosman JA, Ribas A, Lo RS. Nazarian R, et al. Among authors: chodon t. Nature. 2010 Dec 16;468(7326):973-7. doi: 10.1038/nature09626. Epub 2010 Nov 24. Nature. 2010. PMID: 21107323 Free PMC article.

2

The oncogenic BRAF kinase inhibitor PLX4032/RG7204 does not affect the viability or function of human lymphocytes across a wide range of concentrations.

Comin-Anduix B, Chodon T, Sazegar H, Matsunaga D, Mock S, Jalil J, Escuin-Ordinas H, Chmielowski B, Koya RC, Ribas A. Comin-Anduix B, et al. Among authors: chodon t. Clin Cancer Res. 2010 Dec 15;16(24):6040-8. doi: 10.1158/1078-0432.CCR-10-1911. Clin Cancer Res. 2010. PMID: 21169256 Free PMC article.

3

Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance.

Shi H, Moriceau G, Kong X, Lee MK, Lee H, Koya RC, Ng C, Chodon T, Scolyer RA, Dahlman KB, Sosman JA, Kefford RF, Long GV, Nelson SF, Ribas A, Lo RS. Shi H, et al. Among authors: chodon t. Nat Commun. 2012 Mar 6;3:724. doi: 10.1038/ncomms1727. Nat Commun. 2012. PMID: 22395615 Free PMC article.

4

A novel AKT1 mutant amplifies an adaptive melanoma response to BRAF inhibition.

Shi H, Hong A, Kong X, Koya RC, Song C, Moriceau G, Hugo W, Yu CC, Ng C, Chodon T, Scolyer RA, Kefford RF, Ribas A, Long GV, Lo RS. Shi H, et al. Among authors: chodon t. Cancer Discov. 2014 Jan;4(1):69-79. doi: 10.1158/2159-8290.CD-13-0279. Epub 2013 Nov 21. Cancer Discov. 2014. PMID: 24265152 Free PMC article.

5

Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy.

Shi H, Hugo W, Kong X, Hong A, Koya RC, Moriceau G, Chodon T, Guo R, Johnson DB, Dahlman KB, Kelley MC, Kefford RF, Chmielowski B, Glaspy JA, Sosman JA, van Baren N, Long GV, Ribas A, Lo RS. Shi H, et al. Among authors: chodon t. Cancer Discov. 2014 Jan;4(1):80-93. doi: 10.1158/2159-8290.CD-13-0642. Epub 2013 Nov 21. Cancer Discov. 2014. PMID: 24265155 Free PMC article.

6

BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy.

Koya RC, Mok S, Otte N, Blacketor KJ, Comin-Anduix B, Tumeh PC, Minasyan A, Graham NA, Graeber TG, Chodon T, Ribas A. Koya RC, et al. Among authors: chodon t. Cancer Res. 2012 Aug 15;72(16):3928-37. doi: 10.1158/0008-5472.CAN-11-2837. Epub 2012 Jun 12. Cancer Res. 2012. PMID: 22693252 Free PMC article.

7

CTLA4 blockade increases Th17 cells in patients with metastatic melanoma.

von Euw E, Chodon T, Attar N, Jalil J, Koya RC, Comin-Anduix B, Ribas A. von Euw E, et al. Among authors: chodon t. J Transl Med. 2009 May 20;7:35. doi: 10.1186/1479-5876-7-35. J Transl Med. 2009. PMID: 19457253 Free PMC article. Clinical Trial.

8

The impact of ex vivo clinical grade activation protocols on human T-cell phenotype and function for the generation of genetically modified cells for adoptive cell transfer therapy.

Tumeh PC, Koya RC, Chodon T, Graham NA, Graeber TG, Comin-Anduix B, Ribas A. Tumeh PC, et al. Among authors: chodon t. J Immunother. 2010 Oct;33(8):759-68. doi: 10.1097/CJI.0b013e3181f1d644. J Immunother. 2010. PMID: 20842061 Free PMC article.

9

Modulation of cell signaling networks after CTLA4 blockade in patients with metastatic melanoma.

Comin-Anduix B, Sazegar H, Chodon T, Matsunaga D, Jalil J, von Euw E, Escuin-Ordinas H, Balderas R, Chmielowski B, Gomez-Navarro J, Koya RC, Ribas A. Comin-Anduix B, et al. Among authors: chodon t. PLoS One. 2010 Sep 15;5(9):e12711. doi: 10.1371/journal.pone.0012711. PLoS One. 2010. PMID: 20856802 Free PMC article. Clinical Trial.

10

A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells.

Ma C, Fan R, Ahmad H, Shi Q, Comin-Anduix B, Chodon T, Koya RC, Liu CC, Kwong GA, Radu CG, Ribas A, Heath JR. Ma C, et al. Among authors: chodon t. Nat Med. 2011 Jun;17(6):738-43. doi: 10.1038/nm.2375. Epub 2011 May 22. Nat Med. 2011. PMID: 21602800 Free PMC article.

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