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Discovery of a potent, orally bioavailable pyrimidine VLA-4 antagonist effective in a sheep asthma model.
Bioorg Med Chem Lett. 2011 Mar 15;21(6):1741-3. doi: 10.1016/j.bmcl.2011.01.075. Epub 2011 Jan 22.
Bioorg Med Chem Lett. 2011.
PMID: 21316228
Novel oxysterols activate the Hedgehog pathway and induce osteogenesis.
Stappenbeck F, Xiao W, Epperson M, Riley M, Priest A, Huang D, Nguyen K, Jung ME, Thies RS, Farouz F.
Stappenbeck F, et al.
Bioorg Med Chem Lett. 2012 Sep 15;22(18):5893-7. doi: 10.1016/j.bmcl.2012.07.073. Epub 2012 Jul 27.
Bioorg Med Chem Lett. 2012.
PMID: 22901899
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Novel oxysterols have pro-osteogenic and anti-adipogenic effects in vitro and induce spinal fusion in vivo.
Johnson JS, Meliton V, Kim WK, Lee KB, Wang JC, Nguyen K, Yoo D, Jung ME, Atti E, Tetradis S, Pereira RC, Magyar C, Nargizyan T, Hahn TJ, Farouz F, Thies S, Parhami F.
Johnson JS, et al.
J Cell Biochem. 2011 Jun;112(6):1673-84. doi: 10.1002/jcb.23082.
J Cell Biochem. 2011.
PMID: 21503957
Free PMC article.
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