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Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550).
J Immunol. 2011 Apr 1;186(7):4234-43. doi: 10.4049/jimmunol.1003668. Epub 2011 Mar 7.
J Immunol. 2011.
PMID: 21383241
Free PMC article.
Tofacitinib suppresses antibody responses to protein therapeutics in murine hosts.
Onda M, Ghoreschi K, Steward-Tharp S, Thomas C, O'Shea JJ, Pastan IH, FitzGerald DJ.
Onda M, et al.
J Immunol. 2014 Jul 1;193(1):48-55. doi: 10.4049/jimmunol.1400063. Epub 2014 Jun 2.
J Immunol. 2014.
PMID: 24890727
Free PMC article.
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New insights into T cell biology and T cell-directed therapy for autoimmunity, inflammation, and immunosuppression.
Steward-Tharp SM, Song YJ, Siegel RM, O'Shea JJ.
Steward-Tharp SM, et al.
Ann N Y Acad Sci. 2010 Jan;1183:123-48. doi: 10.1111/j.1749-6632.2009.05124.x.
Ann N Y Acad Sci. 2010.
PMID: 20146712
Free PMC article.
Review.
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Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5.
Yang XP, Ghoreschi K, Steward-Tharp SM, Rodriguez-Canales J, Zhu J, Grainger JR, Hirahara K, Sun HW, Wei L, Vahedi G, Kanno Y, O'Shea JJ, Laurence A.
Yang XP, et al. Among authors: steward tharp sm.
Nat Immunol. 2011 Mar;12(3):247-54. doi: 10.1038/ni.1995. Epub 2011 Jan 30.
Nat Immunol. 2011.
PMID: 21278738
Free PMC article.
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Signal transduction and Th17 cell differentiation.
O'Shea JJ, Steward-Tharp SM, Laurence A, Watford WT, Wei L, Adamson AS, Fan S.
O'Shea JJ, et al. Among authors: steward tharp sm.
Microbes Infect. 2009 Apr;11(5):599-611. doi: 10.1016/j.micinf.2009.04.007. Epub 2009 Apr 18.
Microbes Infect. 2009.
PMID: 19379825
Free PMC article.
Review.
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A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3.
Steward-Tharp SM, Laurence A, Kanno Y, Kotlyar A, Villarino AV, Sciume G, Kuchen S, Resch W, Wohlfert EA, Jiang K, Hirahara K, Vahedi G, Sun HW, Feigenbaum L, Milner JD, Holland SM, Casellas R, Powrie F, O'Shea JJ.
Steward-Tharp SM, et al.
Blood. 2014 May 8;123(19):2978-87. doi: 10.1182/blood-2013-09-523167. Epub 2014 Mar 14.
Blood. 2014.
PMID: 24632714
Free PMC article.
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IL-12-Induced Immune Suppressive Deficit During CD8+ T-Cell Differentiation.
Renavikar PS, Sinha S, Brate AA, Borcherding N, Crawford MP, Steward-Tharp SM, Karandikar NJ.
Renavikar PS, et al. Among authors: steward tharp sm.
Front Immunol. 2020 Oct 28;11:568630. doi: 10.3389/fimmu.2020.568630. eCollection 2020.
Front Immunol. 2020.
PMID: 33193343
Free PMC article.
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Altered expression of SIRPγ on the T-cells of relapsing remitting multiple sclerosis and type 1 diabetes patients could potentiate effector responses from T-cells.
Sinha S, Renavikar PS, Crawford MP, Steward-Tharp SM, Brate A, Tsalikian E, Tansey M, Shivapour ET, Cho T, Kamholz J, Karandikar NJ.
Sinha S, et al. Among authors: steward tharp sm.
PLoS One. 2020 Aug 27;15(8):e0238070. doi: 10.1371/journal.pone.0238070. eCollection 2020.
PLoS One. 2020.
PMID: 32853219
Free PMC article.
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