Medema JP - Search Results

1

Development and characterization of APRIL antagonistic monoclonal antibodies for treatment of B-cell lymphomas.

Guadagnoli M, Kimberley FC, Phan U, Cameron K, Vink PM, Rodermond H, Eldering E, Kater AP, van Eenennaam H, Medema JP. Guadagnoli M, et al. Among authors: medema jp. Blood. 2011 Jun 23;117(25):6856-65. doi: 10.1182/blood-2011-01-330852. Epub 2011 May 4. Blood. 2011. PMID: 21543761 Free article.

2

"APRIL hath put a spring of youth in everything": Relevance of APRIL for survival.

Kimberley FC, Hahne M, Medema JP. Kimberley FC, et al. Among authors: medema jp. J Cell Physiol. 2009 Jan;218(1):1-8. doi: 10.1002/jcp.21561. J Cell Physiol. 2009. PMID: 18726990 Review.

3

The proteoglycan (heparan sulfate proteoglycan) binding domain of APRIL serves as a platform for ligand multimerization and cross-linking.

Kimberley FC, van Bostelen L, Cameron K, Hardenberg G, Marquart JA, Hahne M, Medema JP. Kimberley FC, et al. Among authors: medema jp. FASEB J. 2009 May;23(5):1584-95. doi: 10.1096/fj.08-124669. Epub 2009 Jan 13. FASEB J. 2009. PMID: 19141538

4

APRIL in B-cell malignancies and autoimmunity.

Kimberley FC, Medema JP, Hahne M. Kimberley FC, et al. Among authors: medema jp. Results Probl Cell Differ. 2009;49:161-82. doi: 10.1007/400_2008_19. Results Probl Cell Differ. 2009. PMID: 19142624 Review.

5

A proliferation-inducing ligand (APRIL): the development of antagonistic agents as potential therapeutics and deciphering the role of heparan sulphate proteoglycans (HSPGs) in APRIL Signalling.

Kimberley F, Guadagnoli M, van Eenennaam H, Medema JP. Kimberley F, et al. Among authors: medema jp. Adv Exp Med Biol. 2011;691:501-6. doi: 10.1007/978-1-4419-6612-4_52. Adv Exp Med Biol. 2011. PMID: 21153355 No abstract available.

6

Disruption of heparan sulfate proteoglycan conformation perturbs B-cell maturation and APRIL-mediated plasma cell survival.

Reijmers RM, Groen RW, Kuil A, Weijer K, Kimberley FC, Medema JP, van Kuppevelt TH, Li JP, Spaargaren M, Pals ST. Reijmers RM, et al. Among authors: medema jp. Blood. 2011 Jun 9;117(23):6162-71. doi: 10.1182/blood-2010-12-325522. Epub 2011 Apr 6. Blood. 2011. PMID: 21471524 Free article.

7

The design and characterization of receptor-selective APRIL variants.

Kimberley FC, van der Sloot AM, Guadagnoli M, Cameron K, Schneider P, Marquart JA, Versloot M, Serrano L, Medema JP. Kimberley FC, et al. Among authors: medema jp. J Biol Chem. 2012 Oct 26;287(44):37434-46. doi: 10.1074/jbc.M112.406090. Epub 2012 Sep 7. J Biol Chem. 2012. PMID: 22961987 Free PMC article.

8

Chronic lymphocytic leukemia disease progression is accelerated by APRIL-TACI interaction in the TCL1 transgenic mouse model.

Lascano V, Guadagnoli M, Schot JG, Luijks DM, Guikema JE, Cameron K, Hahne M, Pals S, Slinger E, Kipps TJ, van Oers MH, Eldering E, Medema JP, Kater AP. Lascano V, et al. Among authors: medema jp. Blood. 2013 Dec 5;122(24):3960-3. doi: 10.1182/blood-2013-04-497693. Epub 2013 Oct 7. Blood. 2013. PMID: 24100449 Free PMC article.

9

The TNF family member APRIL promotes colorectal tumorigenesis.

Lascano V, Zabalegui LF, Cameron K, Guadagnoli M, Jansen M, Burggraaf M, Versloot M, Rodermond H, van der Loos C, Carvalho-Pinto CE, Kalthoff H, Medema JP, Hahne M. Lascano V, et al. Among authors: medema jp. Cell Death Differ. 2012 Nov;19(11):1826-35. doi: 10.1038/cdd.2012.68. Epub 2012 Jun 15. Cell Death Differ. 2012. PMID: 22705846 Free PMC article.

10

Targeting colorectal cancer stem cells with inducible caspase-9.

Kemper K, Rodermond H, Colak S, Grandela C, Medema JP. Kemper K, et al. Among authors: medema jp. Apoptosis. 2012 May;17(5):528-37. doi: 10.1007/s10495-011-0692-z. Apoptosis. 2012. PMID: 22223359 Free PMC article.

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