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Prolonged prothrombin time after recombinant activated factor VII therapy in critically bleeding trauma patients is associated with adverse outcomes.
McMullin NR, Wade CE, Holcomb JB, Nielsen TG, Rossaint R, Riou B, Rizoli SB, Kluger Y, Choong PI, Warren B, Tortella BJ, Boffard KD; NovoSeven Trauma Study Group. McMullin NR, et al. Among authors: tortella bj. J Trauma. 2010 Jul;69(1):60-9. doi: 10.1097/TA.0b013e3181e17260. J Trauma. 2010. PMID: 20622579 Clinical Trial.
Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhage.
Hauser CJ, Boffard K, Dutton R, Bernard GR, Croce MA, Holcomb JB, Leppaniemi A, Parr M, Vincent JL, Tortella BJ, Dimsits J, Bouillon B; CONTROL Study Group. Hauser CJ, et al. Among authors: tortella bj. J Trauma. 2010 Sep;69(3):489-500. doi: 10.1097/TA.0b013e3181edf36e. J Trauma. 2010. PMID: 20838118 Clinical Trial.
Challenges to effective research in acute trauma resuscitation: consent and endpoints.
Holcomb JB, Weiskopf R, Champion H, Gould SA, Sauer RM, Brasel K, Bochicchio G, Bulger E, Cotton BA, Davis D, Dutton R, Hauser CJ, Hess JR, Hides GA, Knudson P, MacKenzie E, McGinnis RL, Michalek J, Moore FA, Omert L, Pollock BH, Tortella B, Sugarman J, Schreiber MA, Wade CE. Holcomb JB, et al. Shock. 2011 Feb;35(2):107-13. doi: 10.1097/SHK.0b013e3181f7fd01. Shock. 2011. PMID: 20926987
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