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The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network.
Fareh M, Turchi L, Virolle V, Debruyne D, Almairac F, de-la-Forest Divonne S, Paquis P, Preynat-Seauve O, Krause KH, Chneiweiss H, Virolle T. Fareh M, et al. Cell Death Differ. 2012 Feb;19(2):232-44. doi: 10.1038/cdd.2011.89. Epub 2011 Jul 1. Cell Death Differ. 2012. PMID: 21720384 Free PMC article.
DOCK4 promotes loss of proliferation in glioblastoma progenitor cells through nuclear beta-catenin accumulation and subsequent miR-302-367 cluster expression.
Debruyne DN, Turchi L, Burel-Vandenbos F, Fareh M, Almairac F, Virolle V, Figarella-Branger D, Baeza-Kallee N, Lagadec P, Kubiniek V, Paquis P, Fontaine D, Junier MP, Chneiweiss H, Virolle T. Debruyne DN, et al. Among authors: fareh m. Oncogene. 2018 Jan 11;37(2):241-254. doi: 10.1038/onc.2017.323. Epub 2017 Sep 18. Oncogene. 2018. PMID: 28925399
A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma.
El-Habr EA, Dubois LG, Burel-Vandenbos F, Bogeas A, Lipecka J, Turchi L, Lejeune FX, Coehlo PL, Yamaki T, Wittmann BM, Fareh M, Mahfoudhi E, Janin M, Narayanan A, Morvan-Dubois G, Schmitt C, Verreault M, Oliver L, Sharif A, Pallud J, Devaux B, Puget S, Korkolopoulou P, Varlet P, Ottolenghi C, Plo I, Moura-Neto V, Virolle T, Chneiweiss H, Junier MP. El-Habr EA, et al. Among authors: fareh m. Acta Neuropathol. 2017 Apr;133(4):645-660. doi: 10.1007/s00401-016-1659-5. Epub 2016 Dec 28. Acta Neuropathol. 2017. PMID: 28032215 Free PMC article.
25 results