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HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies.
Fouda GG, Yates NL, Pollara J, Shen X, Overman GR, Mahlokozera T, Wilks AB, Kang HH, Salazar-Gonzalez JF, Salazar MG, Kalilani L, Meshnick SR, Hahn BH, Shaw GM, Lovingood RV, Denny TN, Haynes B, Letvin NL, Ferrari G, Montefiori DC, Tomaras GD, Permar SR; Center for HIV/AIDS Vaccine Immunology. Fouda GG, et al. Among authors: wilks ab. J Virol. 2011 Sep;85(18):9555-67. doi: 10.1128/JVI.05174-11. Epub 2011 Jul 6. J Virol. 2011. PMID: 21734046 Free PMC article.
Limited contribution of mucosal IgA to Simian immunodeficiency virus (SIV)-specific neutralizing antibody response and virus envelope evolution in breast milk of SIV-infected, lactating rhesus monkeys.
Permar SR, Wilks AB, Ehlinger EP, Kang HH, Mahlokozera T, Coffey RT, Carville A, Letvin NL, Seaman MS. Permar SR, et al. Among authors: wilks ab. J Virol. 2010 Aug;84(16):8209-18. doi: 10.1128/JVI.00656-10. Epub 2010 Jun 2. J Virol. 2010. PMID: 20519381 Free PMC article.
Origin and evolution of HIV-1 in breast milk determined by single-genome amplification and sequencing.
Salazar-Gonzalez JF, Salazar MG, Learn GH, Fouda GG, Kang HH, Mahlokozera T, Wilks AB, Lovingood RV, Stacey A, Kalilani L, Meshnick SR, Borrow P, Montefiori DC, Denny TN, Letvin NL, Shaw GM, Hahn BH, Permar SR; Center for HIV/AIDS Vaccine Immunology A0167854. Salazar-Gonzalez JF, et al. Among authors: wilks ab. J Virol. 2011 Mar;85(6):2751-63. doi: 10.1128/JVI.02316-10. Epub 2010 Dec 29. J Virol. 2011. PMID: 21191008 Free PMC article.
Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk.
Fouda GG, Amos JD, Wilks AB, Pollara J, Ray CA, Chand A, Kunz EL, Liebl BE, Whitaker K, Carville A, Smith S, Colvin L, Pickup DJ, Staats HF, Overman G, Eutsey-Lloyd K, Parks R, Chen H, Labranche C, Barnett S, Tomaras GD, Ferrari G, Montefiori DC, Liao HX, Letvin NL, Haynes BF, Permar SR. Fouda GG, et al. Among authors: wilks ab. J Virol. 2013 Jun;87(12):6986-99. doi: 10.1128/JVI.00528-13. Epub 2013 Apr 17. J Virol. 2013. PMID: 23596289 Free PMC article.
Lack of B cell dysfunction is associated with functional, gp120-dominant antibody responses in breast milk of simian immunodeficiency virus-infected African green monkeys.
Amos JD, Wilks AB, Fouda GG, Smith SD, Colvin L, Mahlokozera T, Ho C, Beck K, Overman RG, DeMarco CT, Hodge TL, LaBranche CC, Montefiori DC, Denny TN, Liao HX, Tomaras GD, Moody MA, Permar SR. Amos JD, et al. Among authors: wilks ab. J Virol. 2013 Oct;87(20):11121-34. doi: 10.1128/JVI.01887-13. Epub 2013 Aug 7. J Virol. 2013. PMID: 23926338 Free PMC article.
Robust vaccine-elicited cellular immune responses in breast milk following systemic simian immunodeficiency virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys.
Wilks AB, Christian EC, Seaman MS, Sircar P, Carville A, Gomez CE, Esteban M, Pantaleo G, Barouch DH, Letvin NL, Permar SR. Wilks AB, et al. J Immunol. 2010 Dec 1;185(11):7097-106. doi: 10.4049/jimmunol.1002751. Epub 2010 Nov 1. J Immunol. 2010. PMID: 21041730 Free PMC article.
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