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Mutations and deletions of the TP53 gene predict nonresponse to treatment and poor outcome in first relapse of childhood acute lymphoblastic leukemia.
Hof J, Krentz S, van Schewick C, Körner G, Shalapour S, Rhein P, Karawajew L, Ludwig WD, Seeger K, Henze G, von Stackelberg A, Hagemeier C, Eckert C, Kirschner-Schwabe R. Hof J, et al. Among authors: seeger k. J Clin Oncol. 2011 Aug 10;29(23):3185-93. doi: 10.1200/JCO.2011.34.8144. Epub 2011 Jul 11. J Clin Oncol. 2011. PMID: 21747090
Expression of late cell cycle genes and an increased proliferative capacity characterize very early relapse of childhood acute lymphoblastic leukemia.
Kirschner-Schwabe R, Lottaz C, Tödling J, Rhein P, Karawajew L, Eckert C, von Stackelberg A, Ungethüm U, Kostka D, Kulozik AE, Ludwig WD, Henze G, Spang R, Hagemeier C, Seeger K. Kirschner-Schwabe R, et al. Among authors: seeger k. Clin Cancer Res. 2006 Aug 1;12(15):4553-61. doi: 10.1158/1078-0432.CCR-06-0235. Clin Cancer Res. 2006. PMID: 16899601
High VLA-4 expression is associated with adverse outcome and distinct gene expression changes in childhood B-cell precursor acute lymphoblastic leukemia at first relapse.
Shalapour S, Hof J, Kirschner-Schwabe R, Bastian L, Eckert C, Prada J, Henze G, von Stackelberg A, Seeger K. Shalapour S, et al. Among authors: seeger k. Haematologica. 2011 Nov;96(11):1627-35. doi: 10.3324/haematol.2011.047993. Epub 2011 Aug 9. Haematologica. 2011. PMID: 21828124 Free PMC article. Clinical Trial.
Minimal residual disease analysis by eight-color flow cytometry in relapsed childhood acute lymphoblastic leukemia.
Karawajew L, Dworzak M, Ratei R, Rhein P, Gaipa G, Buldini B, Basso G, Hrusak O, Ludwig WD, Henze G, Seeger K, von Stackelberg A, Mejstrikova E, Eckert C. Karawajew L, et al. Among authors: seeger k. Haematologica. 2015 Jul;100(7):935-44. doi: 10.3324/haematol.2014.116707. Epub 2015 May 22. Haematologica. 2015. PMID: 26001791 Free PMC article. Clinical Trial.
Protection of mice against Philadelphia chromosome-positive acute lymphoblastic leukemia by cell-based vaccination using nonviral, minimalistic expression vectors and immunomodulatory oligonucleotides.
Köchling J, König-Merediz SA, Stripecke R, Buchwald D, Korte A, Von Einsiedel HG, Sack F, Henze G, Seeger K, Wittig B, Schmidt M. Köchling J, et al. Among authors: seeger k. Clin Cancer Res. 2003 Aug 1;9(8):3142-9. Clin Cancer Res. 2003. PMID: 12912966
221 results