Loland CJ - Search Results

1

SLC6 neurotransmitter transporters: structure, function, and regulation.

Kristensen AS, Andersen J, Jørgensen TN, Sørensen L, Eriksen J, Loland CJ, Strømgaard K, Gether U. Kristensen AS, et al. Among authors: loland cj. Pharmacol Rev. 2011 Sep;63(3):585-640. doi: 10.1124/pr.108.000869. Epub 2011 Jul 13. Pharmacol Rev. 2011. PMID: 21752877 Review.

2

Modifications to 1-(4-(2-Bis(4-fluorophenyl)methyl)sulfinyl)alkyl Alicyclic Amines That Improve Metabolic Stability and Retain an Atypical DAT Inhibitor Profile.

Okorom AV, Camacho-Hernandez GA, Salomon K, Lee KH, Ku TC, Cao J, Won SJ, Friedman J, Lam J, Paule J, Rais R, Klein B, Xi ZX, Shi L, Loland CJ, Newman AH. Okorom AV, et al. Among authors: loland cj. J Med Chem. 2024 Jan 11;67(1):709-727. doi: 10.1021/acs.jmedchem.3c02037. Epub 2023 Dec 20. J Med Chem. 2024. PMID: 38117239

3

Defining proximity relationships in the tertiary structure of the dopamine transporter. Identification of a conserved glutamic acid as a third coordinate in the endogenous Zn(2+)-binding site.

Loland CJ, Norregaard L, Gether U. Loland CJ, et al. J Biol Chem. 1999 Dec 24;274(52):36928-34. doi: 10.1074/jbc.274.52.36928. J Biol Chem. 1999. PMID: 10601246 Free article.

4

Structural probing of a microdomain in the dopamine transporter by engineering of artificial Zn2+ binding sites.

Norregaard L, Visiers I, Loland CJ, Ballesteros J, Weinstein H, Gether U. Norregaard L, et al. Among authors: loland cj. Biochemistry. 2000 Dec 26;39(51):15836-46. doi: 10.1021/bi0018335. Biochemistry. 2000. PMID: 11123909

5

Delineating structure-function relationships in the dopamine transporter from natural and engineered Zn2+ binding sites.

Gether U, Norregaard L, Loland CJ. Gether U, et al. Among authors: loland cj. Life Sci. 2001 Apr 6;68(19-20):2187-98. doi: 10.1016/s0024-3205(01)01005-0. Life Sci. 2001. PMID: 11358327

6

Engineered Zn(2+) switches in the gamma-aminobutyric acid (GABA) transporter-1. Differential effects on GABA uptake and currents.

MacAulay N, Bendahan A, Loland CJ, Zeuthen T, Kanner BI, Gether U. MacAulay N, et al. Among authors: loland cj. J Biol Chem. 2001 Nov 2;276(44):40476-85. doi: 10.1074/jbc.M105578200. Epub 2001 Aug 29. J Biol Chem. 2001. PMID: 11527967 Free article.

7

Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle.

Loland CJ, Norregaard L, Litman T, Gether U. Loland CJ, et al. Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1683-8. doi: 10.1073/pnas.032386299. Epub 2002 Jan 29. Proc Natl Acad Sci U S A. 2002. PMID: 11818545 Free PMC article.

8

N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization.

Granas C, Ferrer J, Loland CJ, Javitch JA, Gether U. Granas C, et al. Among authors: loland cj. J Biol Chem. 2003 Feb 14;278(7):4990-5000. doi: 10.1074/jbc.M205058200. Epub 2002 Dec 2. J Biol Chem. 2003. PMID: 12464618 Free article.

9

Evidence for distinct sodium-, dopamine-, and cocaine-dependent conformational changes in transmembrane segments 7 and 8 of the dopamine transporter.

Norregaard L, Loland CJ, Gether U. Norregaard L, et al. Among authors: loland cj. J Biol Chem. 2003 Aug 15;278(33):30587-96. doi: 10.1074/jbc.M303854200. Epub 2003 May 28. J Biol Chem. 2003. PMID: 12773538 Free article.

10

Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding.

Loland CJ, Grånäs C, Javitch JA, Gether U. Loland CJ, et al. J Biol Chem. 2004 Jan 30;279(5):3228-38. doi: 10.1074/jbc.M304755200. Epub 2003 Nov 3. J Biol Chem. 2004. PMID: 14597628 Free article.

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