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Deletion of the monkeypox virus inhibitor of complement enzymes locus impacts the adaptive immune response to monkeypox virus in a nonhuman primate model of infection.
Estep RD, Messaoudi I, O'Connor MA, Li H, Sprague J, Barron A, Engelmann F, Yen B, Powers MF, Jones JM, Robinson BA, Orzechowska BU, Manoharan M, Legasse A, Planer S, Wilk J, Axthelm MK, Wong SW. Estep RD, et al. Among authors: powers mf. J Virol. 2011 Sep;85(18):9527-42. doi: 10.1128/JVI.00199-11. Epub 2011 Jul 13. J Virol. 2011. PMID: 21752919 Free PMC article.
The presence of the casein kinase II phosphorylation sites of Vpu enhances the CD4(+) T cell loss caused by the simian-human immunodeficiency virus SHIV(KU-lbMC33) in pig-tailed macaques.
Singh DK, Griffin DM, Pacyniak E, Jackson M, Werle MJ, Wisdom B, Sun F, Hout DR, Pinson DM, Gunderson RS, Powers MF, Wong SW, Stephens EB. Singh DK, et al. Among authors: powers mf. Virology. 2003 Sep 1;313(2):435-51. doi: 10.1016/s0042-6822(03)00339-8. Virology. 2003. PMID: 12954211 Free article.
Substitution of the transmembrane domain of Vpu in simian-human immunodeficiency virus (SHIVKU1bMC33) with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques.
Hout DR, Gomez ML, Pacyniak E, Gomez LM, Fegley B, Mulcahy ER, Hill MS, Culley N, Pinson DM, Nothnick W, Powers MF, Wong SW, Stephens EB. Hout DR, et al. Among authors: powers mf. Virology. 2006 Jan 20;344(2):541-59. doi: 10.1016/j.virol.2005.08.022. Epub 2005 Sep 30. Virology. 2006. PMID: 16199074 Free article.
Fusion of the upstream vpu sequences to the env of simian human immunodeficiency virus (SHIV(KU-1bMC33)) results in the synthesis of two envelope precursor proteins, increased numbers of virus particles associated with the cell surface and is pathogenic for pig-tailed macaques.
Hout DR, Gomez ML, Pacyniak E, Mulcahy ER, Gomez LM, Jackson M, Flick M, Fegley B, McCormick C, Wisdom BJ, Culley N, Pinson DM, Powers M, Wong SW, Stephens EB. Hout DR, et al. Virology. 2004 May 20;323(1):91-107. doi: 10.1016/j.virol.2004.02.028. Virology. 2004. PMID: 15165822 Free article.
32 results