Tesmer VM - Search Results

1

An autoinhibitory helix in the C-terminal region of phospholipase C-β mediates Gαq activation.

Lyon AM, Tesmer VM, Dhamsania VD, Thal DM, Gutierrez J, Chowdhury S, Suddala KC, Northup JK, Tesmer JJ. Lyon AM, et al. Among authors: tesmer jj, tesmer vm. Nat Struct Mol Biol. 2011 Aug 7;18(9):999-1005. doi: 10.1038/nsmb.2095. Nat Struct Mol Biol. 2011. PMID: 21822282 Free PMC article.

2

Snapshot of activated G proteins at the membrane: the Galphaq-GRK2-Gbetagamma complex.

Tesmer VM, Kawano T, Shankaranarayanan A, Kozasa T, Tesmer JJ. Tesmer VM, et al. Among authors: tesmer jj. Science. 2005 Dec 9;310(5754):1686-90. doi: 10.1126/science.1118890. Science. 2005. PMID: 16339447

3

The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs.

Lodowski DT, Tesmer VM, Benovic JL, Tesmer JJ. Lodowski DT, et al. Among authors: tesmer jj, tesmer vm. J Biol Chem. 2006 Jun 16;281(24):16785-93. doi: 10.1074/jbc.M601327200. Epub 2006 Apr 13. J Biol Chem. 2006. PMID: 16613860 Free article.

4

Assembly of high order G alpha q-effector complexes with RGS proteins.

Shankaranarayanan A, Thal DM, Tesmer VM, Roman DL, Neubig RR, Kozasa T, Tesmer JJ. Shankaranarayanan A, et al. Among authors: tesmer jj, tesmer vm. J Biol Chem. 2008 Dec 12;283(50):34923-34. doi: 10.1074/jbc.M805860200. Epub 2008 Oct 20. J Biol Chem. 2008. PMID: 18936096 Free PMC article.

5

Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol.

Tesmer JJ, Tesmer VM, Lodowski DT, Steinhagen H, Huber J. Tesmer JJ, et al. Among authors: tesmer vm. J Med Chem. 2010 Feb 25;53(4):1867-70. doi: 10.1021/jm9017515. J Med Chem. 2010. PMID: 20128603 Free PMC article.

6

Heterotrimeric G protein beta1gamma2 subunits change orientation upon complex formation with G protein-coupled receptor kinase 2 (GRK2) on a model membrane.

Boughton AP, Yang P, Tesmer VM, Ding B, Tesmer JJ, Chen Z. Boughton AP, et al. Among authors: tesmer jj, tesmer vm. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):E667-73. doi: 10.1073/pnas.1108236108. Epub 2011 Aug 29. Proc Natl Acad Sci U S A. 2011. PMID: 21876134 Free PMC article.

7

Molecular mechanism for inhibition of g protein-coupled receptor kinase 2 by a selective RNA aptamer.

Tesmer VM, Lennarz S, Mayer G, Tesmer JJ. Tesmer VM, et al. Among authors: tesmer jj. Structure. 2012 Aug 8;20(8):1300-9. doi: 10.1016/j.str.2012.05.002. Epub 2012 Jun 21. Structure. 2012. PMID: 22727813 Free PMC article.

8

Structural and functional analysis of the regulator of G protein signaling 2-gαq complex.

Nance MR, Kreutz B, Tesmer VM, Sterne-Marr R, Kozasa T, Tesmer JJ. Nance MR, et al. Among authors: tesmer jj, tesmer vm. Structure. 2013 Mar 5;21(3):438-48. doi: 10.1016/j.str.2012.12.016. Epub 2013 Feb 21. Structure. 2013. PMID: 23434405 Free PMC article.

9

Dissecting the telomere-inner nuclear membrane interface formed in meiosis.

Pendlebury DF, Fujiwara Y, Tesmer VM, Smith EM, Shibuya H, Watanabe Y, Nandakumar J. Pendlebury DF, et al. Among authors: tesmer vm. Nat Struct Mol Biol. 2017 Dec;24(12):1064-1072. doi: 10.1038/nsmb.3493. Epub 2017 Oct 30. Nat Struct Mol Biol. 2017. PMID: 29083414 Free PMC article.

10

Structural and functional consequences of a disease mutation in the telomere protein TPP1.

Bisht K, Smith EM, Tesmer VM, Nandakumar J. Bisht K, et al. Among authors: tesmer vm. Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13021-13026. doi: 10.1073/pnas.1605685113. Epub 2016 Nov 2. Proc Natl Acad Sci U S A. 2016. PMID: 27807141 Free PMC article.

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