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Assembly of high order G alpha q-effector complexes with RGS proteins.
Shankaranarayanan A, Thal DM, Tesmer VM, Roman DL, Neubig RR, Kozasa T, Tesmer JJ. Shankaranarayanan A, et al. Among authors: thal dm. J Biol Chem. 2008 Dec 12;283(50):34923-34. doi: 10.1074/jbc.M805860200. Epub 2008 Oct 20. J Biol Chem. 2008. PMID: 18936096 Free PMC article.
Phase-plate cryo-EM structure of a class B GPCR-G-protein complex.
Liang YL, Khoshouei M, Radjainia M, Zhang Y, Glukhova A, Tarrasch J, Thal DM, Furness SGB, Christopoulos G, Coudrat T, Danev R, Baumeister W, Miller LJ, Christopoulos A, Kobilka BK, Wootten D, Skiniotis G, Sexton PM. Liang YL, et al. Among authors: thal dm. Nature. 2017 Jun 1;546(7656):118-123. doi: 10.1038/nature22327. Epub 2017 Apr 24. Nature. 2017. PMID: 28437792 Free PMC article.
Cluster cytometry for high-capacity bioanalysis.
Edwards BS, Zhu J, Chen J, Carter MB, Thal DM, Tesmer JJ, Graves SW, Sklar LA. Edwards BS, et al. Among authors: thal dm. Cytometry A. 2012 May;81(5):419-29. doi: 10.1002/cyto.a.22039. Epub 2012 Mar 21. Cytometry A. 2012. PMID: 22438314 Free PMC article.
Structure of the adenosine-bound human adenosine A1 receptor-Gi complex.
Draper-Joyce CJ, Khoshouei M, Thal DM, Liang YL, Nguyen ATN, Furness SGB, Venugopal H, Baltos JA, Plitzko JM, Danev R, Baumeister W, May LT, Wootten D, Sexton PM, Glukhova A, Christopoulos A. Draper-Joyce CJ, et al. Among authors: thal dm. Nature. 2018 Jun;558(7711):559-563. doi: 10.1038/s41586-018-0236-6. Epub 2018 Jun 20. Nature. 2018. PMID: 29925945
Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia.
Draper-Joyce CJ, Bhola R, Wang J, Bhattarai A, Nguyen ATN, Cowie-Kent I, O'Sullivan K, Chia LY, Venugopal H, Valant C, Thal DM, Wootten D, Panel N, Carlsson J, Christie MJ, White PJ, Scammells P, May LT, Sexton PM, Danev R, Miao Y, Glukhova A, Imlach WL, Christopoulos A. Draper-Joyce CJ, et al. Among authors: thal dm. Nature. 2021 Sep;597(7877):571-576. doi: 10.1038/s41586-021-03897-2. Epub 2021 Sep 8. Nature. 2021. PMID: 34497422 Free PMC article.
Selective G protein signaling driven by substance P-neurokinin receptor dynamics.
Harris JA, Faust B, Gondin AB, Dämgen MA, Suomivuori CM, Veldhuis NA, Cheng Y, Dror RO, Thal DM, Manglik A. Harris JA, et al. Among authors: thal dm. Nat Chem Biol. 2022 Jan;18(1):109-115. doi: 10.1038/s41589-021-00890-8. Epub 2021 Oct 28. Nat Chem Biol. 2022. PMID: 34711980 Free PMC article.
40 results