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A novel mutation in CD132 causes X-CID with defective T-cell activation and impaired humoral reactivity.
Kuijpers TW, Baars PA, Aan de Kerk DJ, Jansen MH, Derks IA, Bredius RG, Sanders EA, van der Burg M, Alders M, van Lier RA. Kuijpers TW, et al. Among authors: van lier ra, van der burg m. J Allergy Clin Immunol. 2011 Dec;128(6):1360-1363.e4. doi: 10.1016/j.jaci.2011.07.001. Epub 2011 Aug 9. J Allergy Clin Immunol. 2011. PMID: 21831415 No abstract available.
The cellular immune system comes of age.
van Lier RAW, Kuijpers TW. van Lier RAW, et al. J Allergy Clin Immunol. 2017 Jun;139(6):1793-1794. doi: 10.1016/j.jaci.2017.02.023. Epub 2017 Mar 22. J Allergy Clin Immunol. 2017. PMID: 28342909 No abstract available.
A reversion of an IL2RG mutation in combined immunodeficiency providing competitive advantage to the majority of CD8+ T cells.
Kuijpers TW, van Leeuwen EM, Barendregt BH, Klarenbeek P, aan de Kerk DJ, Baars PA, Jansen MH, de Vries N, van Lier RA, van der Burg M. Kuijpers TW, et al. Among authors: van lier ra, van leeuwen em, van der burg m. Haematologica. 2013 Jul;98(7):1030-8. doi: 10.3324/haematol.2012.077511. Epub 2013 Feb 12. Haematologica. 2013. PMID: 23403317 Free PMC article.
CD20 deficiency in humans results in impaired T cell-independent antibody responses.
Kuijpers TW, Bende RJ, Baars PA, Grummels A, Derks IA, Dolman KM, Beaumont T, Tedder TF, van Noesel CJ, Eldering E, van Lier RA. Kuijpers TW, et al. Among authors: van noesel cj, van lier ra. J Clin Invest. 2010 Jan;120(1):214-22. doi: 10.1172/JCI40231. Epub 2009 Dec 21. J Clin Invest. 2010. PMID: 20038800 Free PMC article.
365 results