Jordan R - Search Results

1

Development of the small-molecule antiviral ST-246 as a smallpox therapeutic.

Grosenbach DW, Jordan R, Hruby DE. Grosenbach DW, et al. Among authors: jordan r. Future Virol. 2011 May;6(5):653-671. doi: 10.2217/fvl.11.27. Future Virol. 2011. PMID: 21837250 Free PMC article.

2

Smallpox antiviral drug development: satisfying the animal efficacy rule.

Jordan R, Hruby D. Jordan R, et al. Expert Rev Anti Infect Ther. 2006 Apr;4(2):277-89. doi: 10.1586/14787210.4.2.277. Expert Rev Anti Infect Ther. 2006. PMID: 16597208 Free PMC article. Review.

3

Immune responses to the smallpox vaccine given in combination with ST-246, a small-molecule inhibitor of poxvirus dissemination.

Grosenbach DW, Jordan R, King DS, Berhanu A, Warren TK, Kirkwood-Watts DL, Tyavanagimatt S, Tan Y, Wilson RL, Jones KF, Hruby DE. Grosenbach DW, et al. Among authors: jordan r. Vaccine. 2008 Feb 13;26(7):933-46. doi: 10.1016/j.vaccine.2007.11.095. Epub 2007 Dec 26. Vaccine. 2008. PMID: 18226434 Free PMC article.

4

Development of ST-246® for Treatment of Poxvirus Infections.

Jordan R, Leeds JM, Tyavanagimatt S, Hruby DE. Jordan R, et al. Viruses. 2010 Nov;2(11):2409-2435. doi: 10.3390/v2112409. Epub 2010 Nov 3. Viruses. 2010. PMID: 21994624 Free PMC article.

5

Efficacy of ST-246 versus lethal poxvirus challenge in immunodeficient mice.

Grosenbach DW, Berhanu A, King DS, Mosier S, Jones KF, Jordan RA, Bolken TC, Hruby DE. Grosenbach DW, et al. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):838-43. doi: 10.1073/pnas.0912134107. Epub 2009 Dec 22. Proc Natl Acad Sci U S A. 2010. PMID: 20080762 Free PMC article.

6

The vaccinia virus F13L YPPL motif is required for efficient release of extracellular enveloped virus.

Honeychurch KM, Yang G, Jordan R, Hruby DE. Honeychurch KM, et al. Among authors: jordan r. J Virol. 2007 Jul;81(13):7310-5. doi: 10.1128/JVI.00034-07. Epub 2007 May 2. J Virol. 2007. PMID: 17475658 Free PMC article.

7

Discovery of small molecule inhibitors of ubiquitin-like poxvirus proteinase I7L using homology modeling and covalent docking approaches.

Katritch V, Byrd CM, Tseitin V, Dai D, Raush E, Totrov M, Abagyan R, Jordan R, Hruby DE. Katritch V, et al. Among authors: jordan r. J Comput Aided Mol Des. 2007 Oct-Nov;21(10-11):549-58. doi: 10.1007/s10822-007-9138-7. Epub 2007 Oct 25. J Comput Aided Mol Des. 2007. PMID: 17960327 Free PMC article.

8

Single-dose safety and pharmacokinetics of ST-246, a novel orthopoxvirus egress inhibitor.

Jordan R, Tien D, Bolken TC, Jones KF, Tyavanagimatt SR, Strasser J, Frimm A, Corrado ML, Strome PG, Hruby DE. Jordan R, et al. Antimicrob Agents Chemother. 2008 May;52(5):1721-7. doi: 10.1128/AAC.01303-07. Epub 2008 Mar 3. Antimicrob Agents Chemother. 2008. PMID: 18316519 Free PMC article. Clinical Trial.

9

ST-246 antiviral efficacy in a nonhuman primate monkeypox model: determination of the minimal effective dose and human dose justification.

Jordan R, Goff A, Frimm A, Corrado ML, Hensley LE, Byrd CM, Mucker E, Shamblin J, Bolken TC, Wlazlowski C, Johnson W, Chapman J, Twenhafel N, Tyavanagimatt S, Amantana A, Chinsangaram J, Hruby DE, Huggins J. Jordan R, et al. Antimicrob Agents Chemother. 2009 May;53(5):1817-22. doi: 10.1128/AAC.01596-08. Epub 2009 Feb 17. Antimicrob Agents Chemother. 2009. PMID: 19223621 Free PMC article. Clinical Trial.

10

Vaccinia virus p37 interacts with host proteins associated with LE-derived transport vesicle biogenesis.

Chen Y, Honeychurch KM, Yang G, Byrd CM, Harver C, Hruby DE, Jordan R. Chen Y, et al. Among authors: jordan r. Virol J. 2009 Apr 28;6:44. doi: 10.1186/1743-422X-6-44. Virol J. 2009. PMID: 19400954 Free PMC article.

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