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Doxazosin induces apoptosis of cells expressing hERG K+ channels.
Thomas D, Bloehs R, Koschny R, Ficker E, Sykora J, Kiehn J, Schlömer K, Gierten J, Kathöfer S, Zitron E, Scholz EP, Kiesecker C, Katus HA, Karle CA. Thomas D, et al. Among authors: gierten j. Eur J Pharmacol. 2008 Jan 28;579(1-3):98-103. doi: 10.1016/j.ejphar.2007.10.051. Epub 2007 Dec 4. Eur J Pharmacol. 2008. PMID: 18054910 Free PMC article.
Carvedilol targets human K2P 3.1 (TASK1) K+ leak channels.
Staudacher K, Staudacher I, Ficker E, Seyler C, Gierten J, Kisselbach J, Rahm AK, Trappe K, Schweizer PA, Becker R, Katus HA, Thomas D. Staudacher K, et al. Among authors: gierten j. Br J Pharmacol. 2011 Jul;163(5):1099-110. doi: 10.1111/j.1476-5381.2011.01319.x. Br J Pharmacol. 2011. PMID: 21410455 Free PMC article.
PKC-dependent activation of human K(2P) 18.1 K(+) channels.
Rahm AK, Gierten J, Kisselbach J, Staudacher I, Staudacher K, Schweizer PA, Becker R, Katus HA, Thomas D. Rahm AK, et al. Among authors: gierten j. Br J Pharmacol. 2012 May;166(2):764-73. doi: 10.1111/j.1476-5381.2011.01813.x. Br J Pharmacol. 2012. PMID: 22168364 Free PMC article.
22 results