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Activation of inwardly rectifying Kir2.x potassium channels by beta 3-adrenoceptors is mediated via different signaling pathways with a predominant role of PKC for Kir2.1 and of PKA for Kir2.2.
Scherer D, Kiesecker C, Kulzer M, Günth M, Scholz EP, Kathöfer S, Thomas D, Maurer M, Kreuzer J, Bauer A, Katus HA, Karle CA, Zitron E. Scherer D, et al. Among authors: karle ca. Naunyn Schmiedebergs Arch Pharmacol. 2007 Jul;375(5):311-22. doi: 10.1007/s00210-007-0167-5. Epub 2007 May 30. Naunyn Schmiedebergs Arch Pharmacol. 2007. PMID: 17534603
Selective noradrenaline reuptake inhibitor atomoxetine directly blocks hERG currents.
Scherer D, Hassel D, Bloehs R, Zitron E, von Löwenstern K, Seyler C, Thomas D, Konrad F, Bürgers HF, Seemann G, Rottbauer W, Katus HA, Karle CA, Scholz EP. Scherer D, et al. Among authors: karle ca. Br J Pharmacol. 2009 Jan;156(2):226-36. doi: 10.1111/j.1476-5381.2008.00018.x. Epub 2009 Jan 16. Br J Pharmacol. 2009. PMID: 19154426 Free PMC article.
81 results