Mezler M - Search Results

1

A β-amyloid oligomer directly modulates P/Q-type calcium currents in Xenopus oocytes.

Mezler M, Barghorn S, Schoemaker H, Gross G, Nimmrich V. Mezler M, et al. Br J Pharmacol. 2012 Mar;165(5):1572-83. doi: 10.1111/j.1476-5381.2011.01646.x. Br J Pharmacol. 2012. PMID: 21883149 Free PMC article.

2

Synthetic Aβ oligomers (Aβ(1-42) globulomer) modulate presynaptic calcium currents: prevention of Aβ-induced synaptic deficits by calcium channel blockers.

Hermann D, Mezler M, Müller MK, Wicke K, Gross G, Draguhn A, Bruehl C, Nimmrich V. Hermann D, et al. Among authors: mezler m. Eur J Pharmacol. 2013 Feb 28;702(1-3):44-55. doi: 10.1016/j.ejphar.2013.01.030. Epub 2013 Jan 30. Eur J Pharmacol. 2013. PMID: 23376566

3

Inhibitors of GlyT1 affect glycine transport via discrete binding sites.

Mezler M, Hornberger W, Mueller R, Schmidt M, Amberg W, Braje W, Ochse M, Schoemaker H, Behl B. Mezler M, et al. Mol Pharmacol. 2008 Dec;74(6):1705-15. doi: 10.1124/mol.108.049312. Epub 2008 Sep 24. Mol Pharmacol. 2008. PMID: 18815213

4

Development and validation of a fluorescence-based HTS assay for the identification of P/Q-type calcium channel blockers.

Mezler M, Hermann D, Swensen AM, Draguhn A, Terstappen GC, Gross G, Schoemaker H, Freiberg G, Pratt S, Gopalakrishnan SM, Nimmrich V. Mezler M, et al. Comb Chem High Throughput Screen. 2012 Jun 1;15(5):372-85. doi: 10.2174/138620712800194503. Comb Chem High Throughput Screen. 2012. PMID: 22272661

5

Establishment of a secondary screening assay for P/Q-type calcium channel blockers.

Hermann D, Mezler M, Swensen AM, Bruehl C, Obergrußerger A, Wicke K, Schoemaker H, Gross G, Draguhn A, Nimmrich V. Hermann D, et al. Among authors: mezler m. Comb Chem High Throughput Screen. 2013 Mar;16(3):233-43. doi: 10.2174/1386207311316030008. Comb Chem High Throughput Screen. 2013. PMID: 23228050

6

Behavioral characterization of the mGlu group II/III receptor antagonist, LY-341495, in animal models of anxiety and depression.

Bespalov AY, van Gaalen MM, Sukhotina IA, Wicke K, Mezler M, Schoemaker H, Gross G. Bespalov AY, et al. Among authors: mezler m. Eur J Pharmacol. 2008 Sep 11;592(1-3):96-102. doi: 10.1016/j.ejphar.2008.06.089. Epub 2008 Jul 2. Eur J Pharmacol. 2008. PMID: 18634781

7

Effects of a positive allosteric modulator of group II metabotropic glutamate receptors, LY487379, on cognitive flexibility and impulsive-like responding in rats.

Nikiforuk A, Popik P, Drescher KU, van Gaalen M, Relo AL, Mezler M, Marek G, Schoemaker H, Gross G, Bespalov A. Nikiforuk A, et al. Among authors: mezler m. J Pharmacol Exp Ther. 2010 Dec;335(3):665-73. doi: 10.1124/jpet.110.170506. Epub 2010 Aug 25. J Pharmacol Exp Ther. 2010. PMID: 20739457

8

NOGO-66 receptor deficient mice show slow acquisition of spatial memory task performance.

van Gaalen MM, Relo AL, Mueller BK, Gross G, Mezler M. van Gaalen MM, et al. Among authors: mezler m. Neurosci Lett. 2012 Feb 21;510(1):58-61. doi: 10.1016/j.neulet.2012.01.004. Epub 2012 Jan 11. Neurosci Lett. 2012. PMID: 22260793

9

Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A-841720, a novel non-competitive mGluR1 receptor antagonist.

El-Kouhen O, Lehto SG, Pan JB, Chang R, Baker SJ, Zhong C, Hollingsworth PR, Mikusa JP, Cronin EA, Chu KL, McGaraughty SP, Uchic ME, Miller LN, Rodell NM, Patel M, Bhatia P, Mezler M, Kolasa T, Zheng GZ, Fox GB, Stewart AO, Decker MW, Moreland RB, Brioni JD, Honore P. El-Kouhen O, et al. Among authors: mezler m. Br J Pharmacol. 2006 Nov;149(6):761-74. doi: 10.1038/sj.bjp.0706877. Epub 2006 Oct 3. Br J Pharmacol. 2006. PMID: 17016515 Free PMC article.

10

Awake rat pharmacological magnetic resonance imaging as a translational pharmacodynamic biomarker: metabotropic glutamate 2/3 agonist modulation of ketamine-induced blood oxygenation level dependence signals.

Chin CL, Upadhyay J, Marek GJ, Baker SJ, Zhang M, Mezler M, Fox GB, Day M. Chin CL, et al. Among authors: mezler m. J Pharmacol Exp Ther. 2011 Mar;336(3):709-15. doi: 10.1124/jpet.110.173880. Epub 2010 Dec 20. J Pharmacol Exp Ther. 2011. PMID: 21172908

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