Rubinsztein DC - Search Results

1

Rubinsztein DC, Mariño G, Kroemer G. Rubinsztein DC, et al. Cell. 2011 Sep 2;146(5):682-95. doi: 10.1016/j.cell.2011.07.030. Cell. 2011. PMID: 21884931 Free article. Review.

2

Raised intracellular glucose concentrations reduce aggregation and cell death caused by mutant huntingtin exon 1 by decreasing mTOR phosphorylation and inducing autophagy.

Ravikumar B, Stewart A, Kita H, Kato K, Duden R, Rubinsztein DC. Ravikumar B, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2003 May 1;12(9):985-94. doi: 10.1093/hmg/ddg109. Hum Mol Genet. 2003. PMID: 12700167

3

Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: implications for mutant huntingtin toxicity.

Luo S, Vacher C, Davies JE, Rubinsztein DC. Luo S, et al. Among authors: rubinsztein dc. J Cell Biol. 2005 May 23;169(4):647-56. doi: 10.1083/jcb.200412071. J Cell Biol. 2005. PMID: 15911879 Free PMC article.

4

Lithium induces autophagy by inhibiting inositol monophosphatase.

Sarkar S, Floto RA, Berger Z, Imarisio S, Cordenier A, Pasco M, Cook LJ, Rubinsztein DC. Sarkar S, et al. Among authors: rubinsztein dc. J Cell Biol. 2005 Sep 26;170(7):1101-11. doi: 10.1083/jcb.200504035. J Cell Biol. 2005. PMID: 16186256 Free PMC article.

5

Autophagy and its possible roles in nervous system diseases, damage and repair.

Rubinsztein DC, DiFiglia M, Heintz N, Nixon RA, Qin ZH, Ravikumar B, Stefanis L, Tolkovsky A. Rubinsztein DC, et al. Autophagy. 2005 Apr;1(1):11-22. doi: 10.4161/auto.1.1.1513. Epub 2005 Apr 30. Autophagy. 2005. PMID: 16874045 Review.

6

Dyneins, autophagy, aggregation and neurodegeneration.

Rubinsztein DC, Ravikumar B, Acevedo-Arozena A, Imarisio S, O'Kane CJ, Brown SD. Rubinsztein DC, et al. Autophagy. 2005 Oct-Dec;1(3):177-8. doi: 10.4161/auto.1.3.2050. Epub 2005 Oct 21. Autophagy. 2005. PMID: 16874055 Review.

7

Role of autophagy in the clearance of mutant huntingtin: a step towards therapy?

Ravikumar B, Rubinsztein DC. Ravikumar B, et al. Among authors: rubinsztein dc. Mol Aspects Med. 2006 Oct-Dec;27(5-6):520-7. doi: 10.1016/j.mam.2006.08.008. Epub 2006 Sep 14. Mol Aspects Med. 2006. PMID: 16973207 Review.

8

Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.

Sarkar S, Davies JE, Huang Z, Tunnacliffe A, Rubinsztein DC. Sarkar S, et al. Among authors: rubinsztein dc. J Biol Chem. 2007 Feb 23;282(8):5641-52. doi: 10.1074/jbc.M609532200. Epub 2006 Dec 20. J Biol Chem. 2007. PMID: 17182613 Free article.

9

Potential therapeutic applications of autophagy.

Rubinsztein DC, Gestwicki JE, Murphy LO, Klionsky DJ. Rubinsztein DC, et al. Nat Rev Drug Discov. 2007 Apr;6(4):304-12. doi: 10.1038/nrd2272. Nat Rev Drug Discov. 2007. PMID: 17396135 Review.

10

Atg5 and Bcl-2 provide novel insights into the interplay between apoptosis and autophagy.

Luo S, Rubinsztein DC. Luo S, et al. Among authors: rubinsztein dc. Cell Death Differ. 2007 Jul;14(7):1247-50. doi: 10.1038/sj.cdd.4402149. Epub 2007 Apr 13. Cell Death Differ. 2007. PMID: 17431417 Review. No abstract available.

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