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Pretreatment with interferon-γ enhances the therapeutic activity of mesenchymal stromal cells in animal models of colitis.
Duijvestein M, Wildenberg ME, Welling MM, Hennink S, Molendijk I, van Zuylen VL, Bosse T, Vos AC, de Jonge-Muller ES, Roelofs H, van der Weerd L, Verspaget HW, Fibbe WE, te Velde AA, van den Brink GR, Hommes DW. Duijvestein M, et al. Among authors: van der weerd l, van den brink gr, van zuylen vl. Stem Cells. 2011 Oct;29(10):1549-58. doi: 10.1002/stem.698. Stem Cells. 2011. PMID: 21898680
In vivo detection of amyloid-β deposits using heavy chain antibody fragments in a transgenic mouse model for Alzheimer's disease.
Nabuurs RJ, Rutgers KS, Welling MM, Metaxas A, de Backer ME, Rotman M, Bacskai BJ, van Buchem MA, van der Maarel SM, van der Weerd L. Nabuurs RJ, et al. Among authors: van buchem ma, van der maarel sm, van der weerd l. PLoS One. 2012;7(6):e38284. doi: 10.1371/journal.pone.0038284. Epub 2012 Jun 4. PLoS One. 2012. PMID: 22675537 Free PMC article.
Polyfluorinated bis-styrylbenzenes as amyloid-β plaque binding ligands.
Nabuurs RJ, Kapoerchan VV, Metaxas A, de Jongh S, de Backer M, Welling MM, Jiskoot W, Windhorst AD, Overkleeft HS, van Buchem MA, Overhand M, van der Weerd L. Nabuurs RJ, et al. Among authors: van buchem ma, van der weerd l. Bioorg Med Chem. 2014 Apr 15;22(8):2469-81. doi: 10.1016/j.bmc.2014.02.054. Epub 2014 Mar 7. Bioorg Med Chem. 2014. PMID: 24657049
Enhanced glutathione PEGylated liposomal brain delivery of an anti-amyloid single domain antibody fragment in a mouse model for Alzheimer's disease.
Rotman M, Welling MM, Bunschoten A, de Backer ME, Rip J, Nabuurs RJ, Gaillard PJ, van Buchem MA, van der Maarel SM, van der Weerd L. Rotman M, et al. Among authors: van buchem ma, van der maarel sm, van der weerd l. J Control Release. 2015 Apr 10;203:40-50. doi: 10.1016/j.jconrel.2015.02.012. Epub 2015 Feb 7. J Control Release. 2015. PMID: 25668771
Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake.
Rotman M, Welling MM, van den Boogaard ML, Moursel LG, van der Graaf LM, van Buchem MA, van der Maarel SM, van der Weerd L. Rotman M, et al. Among authors: van buchem ma, van der maarel sm, van der weerd l, van den boogaard ml, van der graaf lm. Nucl Med Biol. 2015 Aug;42(8):695-702. doi: 10.1016/j.nucmedbio.2015.03.003. Epub 2015 Mar 18. Nucl Med Biol. 2015. PMID: 25960433 Free article.
Bis-pyridylethenyl benzene as novel backbone for amyloid-β binding compounds.
Nabuurs RJ, Kapoerchan VV, Metaxas A, Hafith S, de Backer M, Welling MM, Jiskoot W, van den Nieuwendijk AM, Windhorst AD, Overkleeft HS, van Buchem MA, Overhand M, van der Weerd L. Nabuurs RJ, et al. Among authors: van buchem ma, van der weerd l, van den nieuwendijk am. Bioorg Med Chem. 2016 Dec 1;24(23):6139-6148. doi: 10.1016/j.bmc.2016.05.022. Epub 2016 May 18. Bioorg Med Chem. 2016. PMID: 27838168
MRI in animal models of psychiatric disorders.
Poole DS, Oitzl MS, van der Weerd L. Poole DS, et al. Among authors: van der weerd l. Methods Mol Biol. 2011;771:309-35. doi: 10.1007/978-1-61779-219-9_17. Methods Mol Biol. 2011. PMID: 21874486
Iron accumulation induces oxidative stress, while depressing inflammatory polarization in human iPSC-derived microglia.
Kenkhuis B, van Eekeren M, Parfitt DA, Ariyurek Y, Banerjee P, Priller J, van der Weerd L, van Roon-Mom WMC. Kenkhuis B, et al. Among authors: van der weerd l, van eekeren m, van roon mom wmc. Stem Cell Reports. 2022 Jun 14;17(6):1351-1365. doi: 10.1016/j.stemcr.2022.04.006. Epub 2022 May 5. Stem Cell Reports. 2022. PMID: 35523178 Free PMC article.
116 results