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Page 1
Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells.
Diouf B, Cheng Q, Krynetskaia NF, Yang W, Cheok M, Pei D, Fan Y, Cheng C, Krynetskiy EY, Geng H, Chen S, Thierfelder WE, Mullighan CG, Downing JR, Hsieh P, Pui CH, Relling MV, Evans WE. Diouf B, et al. Among authors: thierfelder we. Nat Med. 2011 Sep 25;17(10):1298-303. doi: 10.1038/nm.2430. Nat Med. 2011. PMID: 21946537 Free PMC article.
NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells.
Paugh SW, Bonten EJ, Savic D, Ramsey LB, Thierfelder WE, Gurung P, Malireddi RK, Actis M, Mayasundari A, Min J, Coss DR, Laudermilk LT, Panetta JC, McCorkle JR, Fan Y, Crews KR, Stocco G, Wilkinson MR, Ferreira AM, Cheng C, Yang W, Karol SE, Fernandez CA, Diouf B, Smith C, Hicks JK, Zanut A, Giordanengo A, Crona D, Bianchi JJ, Holmfeldt L, Mullighan CG, den Boer ML, Pieters R, Jeha S, Dunwell TL, Latif F, Bhojwani D, Carroll WL, Pui CH, Myers RM, Guy RK, Kanneganti TD, Relling MV, Evans WE. Paugh SW, et al. Among authors: thierfelder we. Nat Genet. 2015 Jun;47(6):607-14. doi: 10.1038/ng.3283. Epub 2015 May 4. Nat Genet. 2015. PMID: 25938942 Free PMC article.
PACSIN2 polymorphism influences TPMT activity and mercaptopurine-related gastrointestinal toxicity.
Stocco G, Yang W, Crews KR, Thierfelder WE, Decorti G, Londero M, Franca R, Rabusin M, Valsecchi MG, Pei D, Cheng C, Paugh SW, Ramsey LB, Diouf B, McCorkle JR, Jones TS, Pui CH, Relling MV, Evans WE. Stocco G, et al. Among authors: thierfelder we. Hum Mol Genet. 2012 Nov 1;21(21):4793-804. doi: 10.1093/hmg/dds302. Epub 2012 Jul 30. Hum Mol Genet. 2012. PMID: 22846425 Free PMC article.
Defective lymphoid development in mice lacking Jak3.
Nosaka T, van Deursen JM, Tripp RA, Thierfelder WE, Witthuhn BA, McMickle AP, Doherty PC, Grosveld GC, Ihle JN. Nosaka T, et al. Among authors: thierfelder we. Science. 1995 Nov 3;270(5237):800-2. doi: 10.1126/science.270.5237.800. Science. 1995. PMID: 7481769
Jaks and Stats in cytokine signaling.
Ihle JN, Nosaka T, Thierfelder W, Quelle FW, Shimoda K. Ihle JN, et al. Stem Cells. 1997;15 Suppl 1:105-11; discussion 112. doi: 10.1002/stem.5530150814. Stem Cells. 1997. PMID: 9368330 Review.
Signaling by the cytokine receptor superfamily.
Ihle JN, Thierfelder W, Teglund S, Stravopodis D, Wang D, Feng J, Parganas E. Ihle JN, et al. Ann N Y Acad Sci. 1998 Dec 11;865:1-9. doi: 10.1111/j.1749-6632.1998.tb11157.x. Ann N Y Acad Sci. 1998. PMID: 9927991 Review.
15 results