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Plasma letrozole concentrations in postmenopausal women with breast cancer are associated with CYP2A6 genetic variants, body mass index, and age.
Desta Z, Kreutz Y, Nguyen AT, Li L, Skaar T, Kamdem LK, Henry NL, Hayes DF, Storniolo AM, Stearns V, Hoffmann E, Tyndale RF, Flockhart DA. Desta Z, et al. Clin Pharmacol Ther. 2011 Nov;90(5):693-700. doi: 10.1038/clpt.2011.174. Epub 2011 Oct 5. Clin Pharmacol Ther. 2011. PMID: 21975350 Free PMC article. Clinical Trial.
Estrogen receptor genotypes, menopausal status, and the lipid effects of tamoxifen.
Ntukidem NI, Nguyen AT, Stearns V, Rehman M, Schott A, Skaar T, Jin Y, Blanche P, Li L, Lemler S, Hayden J, Krauss RM, Desta Z, Flockhart DA, Hayes DF; Consortium on Breast Cancer Pharmacogenomics. Ntukidem NI, et al. Among authors: desta z. Clin Pharmacol Ther. 2008 May;83(5):702-10. doi: 10.1038/sj.clpt.6100343. Epub 2007 Aug 22. Clin Pharmacol Ther. 2008. PMID: 17713466 Free PMC article. Clinical Trial.
Cytochrome P450 2D6 activity predicts discontinuation of tamoxifen therapy in breast cancer patients.
Rae JM, Sikora MJ, Henry NL, Li L, Kim S, Oesterreich S, Skaar TC, Nguyen AT, Desta Z, Storniolo AM, Flockhart DA, Hayes DF, Stearns V; COBRA investigators. Rae JM, et al. Among authors: desta z. Pharmacogenomics J. 2009 Aug;9(4):258-64. doi: 10.1038/tpj.2009.14. Epub 2009 May 5. Pharmacogenomics J. 2009. PMID: 19421167 Free PMC article. Clinical Trial.
Estrogen receptor genotypes, menopausal status, and the effects of tamoxifen on lipid levels: revised and updated results.
Hayes DF, Skaar TC, Rae JM, Henry NL, Nguyen AT, Stearns V, Li L, Philips S, Desta Z, Flockhart DA; Consortium on Breast Cancer Pharmacogenomics (COBRA). Hayes DF, et al. Among authors: desta z. Clin Pharmacol Ther. 2010 Nov;88(5):626-9. doi: 10.1038/clpt.2010.143. Epub 2010 Sep 8. Clin Pharmacol Ther. 2010. PMID: 20827267 Free PMC article. Clinical Trial.
183 results