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Plasma letrozole concentrations in postmenopausal women with breast cancer are associated with CYP2A6 genetic variants, body mass index, and age.
Desta Z, Kreutz Y, Nguyen AT, Li L, Skaar T, Kamdem LK, Henry NL, Hayes DF, Storniolo AM, Stearns V, Hoffmann E, Tyndale RF, Flockhart DA. Desta Z, et al. Among authors: flockhart da. Clin Pharmacol Ther. 2011 Nov;90(5):693-700. doi: 10.1038/clpt.2011.174. Epub 2011 Oct 5. Clin Pharmacol Ther. 2011. PMID: 21975350 Free PMC article. Clinical Trial.
Estrogen receptor genotypes, menopausal status, and the lipid effects of tamoxifen.
Ntukidem NI, Nguyen AT, Stearns V, Rehman M, Schott A, Skaar T, Jin Y, Blanche P, Li L, Lemler S, Hayden J, Krauss RM, Desta Z, Flockhart DA, Hayes DF; Consortium on Breast Cancer Pharmacogenomics. Ntukidem NI, et al. Among authors: flockhart da. Clin Pharmacol Ther. 2008 May;83(5):702-10. doi: 10.1038/sj.clpt.6100343. Epub 2007 Aug 22. Clin Pharmacol Ther. 2008. PMID: 17713466 Free PMC article. Clinical Trial.
Clinically available pharmacogenomics tests.
Flockhart DA, Skaar T, Berlin DS, Klein TE, Nguyen AT. Flockhart DA, et al. Clin Pharmacol Ther. 2009 Jul;86(1):109-13. doi: 10.1038/clpt.2009.39. Epub 2009 Apr 15. Clin Pharmacol Ther. 2009. PMID: 19369936 Free PMC article. Review.
Modeling hot flushes and quality of life in breast cancer survivors.
Rand KL, Otte JL, Flockhart D, Hayes D, Storniolo AM, Stearns V, Henry NL, Nguyen A, Lemler S, Hayden J, Jeter S, Carpenter JS. Rand KL, et al. Climacteric. 2011 Feb;14(1):171-80. doi: 10.3109/13697131003717070. Epub 2010 May 7. Climacteric. 2011. PMID: 20450413 Free PMC article. Clinical Trial.
249 results