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HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus.
Feng X, Krishnan K, Richie DL, Aimanianda V, Hartl L, Grahl N, Powers-Fletcher MV, Zhang M, Fuller KK, Nierman WC, Lu LJ, Latgé JP, Woollett L, Newman SL, Cramer RA Jr, Rhodes JC, Askew DS. Feng X, et al. Among authors: grahl n. PLoS Pathog. 2011 Oct;7(10):e1002330. doi: 10.1371/journal.ppat.1002330. Epub 2011 Oct 20. PLoS Pathog. 2011. PMID: 22028661 Free PMC article.
A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus.
Willger SD, Puttikamonkul S, Kim KH, Burritt JB, Grahl N, Metzler LJ, Barbuch R, Bard M, Lawrence CB, Cramer RA Jr. Willger SD, et al. Among authors: grahl n. PLoS Pathog. 2008 Nov;4(11):e1000200. doi: 10.1371/journal.ppat.1000200. Epub 2008 Nov 7. PLoS Pathog. 2008. PMID: 18989462 Free PMC article.
Trehalose 6-phosphate phosphatase is required for cell wall integrity and fungal virulence but not trehalose biosynthesis in the human fungal pathogen Aspergillus fumigatus.
Puttikamonkul S, Willger SD, Grahl N, Perfect JR, Movahed N, Bothner B, Park S, Paderu P, Perlin DS, Cramer RA Jr. Puttikamonkul S, et al. Among authors: grahl n. Mol Microbiol. 2010 Aug;77(4):891-911. doi: 10.1111/j.1365-2958.2010.07254.x. Epub 2010 Jun 9. Mol Microbiol. 2010. PMID: 20545865 Free PMC article.
27 results