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Kisspeptin signaling is indispensable for neurokinin B, but not glutamate, stimulation of gonadotropin secretion in mice.
García-Galiano D, van Ingen Schenau D, Leon S, Krajnc-Franken MA, Manfredi-Lozano M, Romero-Ruiz A, Navarro VM, Gaytan F, van Noort PI, Pinilla L, Blomenröhr M, Tena-Sempere M. García-Galiano D, et al. Among authors: van ingen schenau d, van noort pi. Endocrinology. 2012 Jan;153(1):316-28. doi: 10.1210/en.2011-1260. Epub 2011 Nov 8. Endocrinology. 2012. PMID: 22067321
Histone deacetylase inhibition sensitizes p53-deficient B-cell precursor acute lymphoblastic leukemia to chemotherapy.
Cox WPJ, Evander N, Van Ingen Schenau DS, Stoll GR, Anderson N, De Groot L, Grünewald KJT, Hagelaar R, Butler M, Kuiper RP, Van der Meer LT, Van Leeuwen FN. Cox WPJ, et al. Among authors: van ingen schenau ds. Haematologica. 2023 Dec 21. doi: 10.3324/haematol.2023.284101. Online ahead of print. Haematologica. 2023. PMID: 38124624 Free article.
Human CD34+-derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8+ T cell and NK cell responses in vitro and in vivo.
van Eck van der Sluijs J, van Ens D, Brummelman J, Heister D, Sareen A, Truijen L, van Ingen Schenau DS, Heemskerk MHM, Griffioen M, Kester MGD, Schaap NPM, Jansen JH, van der Waart AB, Dolstra H, Hobo W. van Eck van der Sluijs J, et al. Among authors: van ingen schenau ds. Cell Mol Life Sci. 2023 Sep 20;80(10):298. doi: 10.1007/s00018-023-04923-4. Cell Mol Life Sci. 2023. PMID: 37728691 Free PMC article.
Oncogenic TYK2 P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade.
Woess K, Macho-Maschler S, Van Ingen Schenau DS, Butler M, Lassnig C, Valcanover D, Poelzl A, Meissl K, Maurer B, Brandstoetter T, Vogl C, Koren A, Kubicek S, Orlova A, Moriggl R, Strobl B, Sexl V, Van Leeuwen FN, Kuiper RP, Mueller M. Woess K, et al. Among authors: van ingen schenau ds. Haematologica. 2023 Apr 1;108(4):993-1005. doi: 10.3324/haematol.2021.279848. Haematologica. 2023. PMID: 35021603 Free PMC article.
BTK inhibition sensitizes acute lymphoblastic leukemia to asparaginase by suppressing the amino acid response pathway.
Butler M, van Ingen Schenau DS, Yu J, Jenni S, Dobay MP, Hagelaar R, Vervoort BMT, Tee TM, Hoff FW, Meijerink JP, Kornblau SM, Bornhauser B, Bourquin JP, Kuiper RP, van der Meer LT, van Leeuwen FN. Butler M, et al. Among authors: van ingen schenau ds. Blood. 2021 Dec 9;138(23):2383-2395. doi: 10.1182/blood.2021011787. Blood. 2021. PMID: 34280258 Free PMC article. Clinical Trial.
The transcriptional repressor SNAI2 impairs neuroblastoma differentiation and inhibits response to retinoic acid therapy.
Vrenken KS, Vervoort BMT, van Ingen Schenau DS, Derks YHW, van Emst L, Grytsenko PG, Middelbeek JAJ, van Leeuwen FN. Vrenken KS, et al. Among authors: van ingen schenau ds. Biochim Biophys Acta Mol Basis Dis. 2020 Mar 1;1866(3):165644. doi: 10.1016/j.bbadis.2019.165644. Epub 2019 Dec 17. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 31862304 Free article.
Tumor suppressor BTG1 limits activation of BCL6 expression downstream of ETV6-RUNX1.
Tijchon E, van Emst L, Yuniati L, van Ingen Schenau D, Gerritsen M, van der Meer LT, Williams O, Hoogerbrugge PM, Scheijen B, van Leeuwen FN. Tijchon E, et al. Among authors: van ingen schenau d. Exp Hematol. 2018 Apr;60:57-62.e3. doi: 10.1016/j.exphem.2018.01.006. Epub 2018 Feb 8. Exp Hematol. 2018. PMID: 29408281 Free article.
Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients.
Scheijen B, Boer JM, Marke R, Tijchon E, van Ingen Schenau D, Waanders E, van Emst L, van der Meer LT, Pieters R, Escherich G, Horstmann MA, Sonneveld E, Venn N, Sutton R, Dalla-Pozza L, Kuiper RP, Hoogerbrugge PM, den Boer ML, van Leeuwen FN. Scheijen B, et al. Among authors: van ingen schenau d. Haematologica. 2017 Mar;102(3):541-551. doi: 10.3324/haematol.2016.153023. Epub 2016 Dec 15. Haematologica. 2017. PMID: 27979924 Free PMC article.
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