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Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
McLellan JS, Pancera M, Carrico C, Gorman J, Julien JP, Khayat R, Louder R, Pejchal R, Sastry M, Dai K, O'Dell S, Patel N, Shahzad-ul-Hussan S, Yang Y, Zhang B, Zhou T, Zhu J, Boyington JC, Chuang GY, Diwanji D, Georgiev I, Kwon YD, Lee D, Louder MK, Moquin S, Schmidt SD, Yang ZY, Bonsignori M, Crump JA, Kapiga SH, Sam NE, Haynes BF, Burton DR, Koff WC, Walker LM, Phogat S, Wyatt R, Orwenyo J, Wang LX, Arthos J, Bewley CA, Mascola JR, Nabel GJ, Schief WR, Ward AB, Wilson IA, Kwong PD. McLellan JS, et al. Among authors: burton dr. Nature. 2011 Nov 23;480(7377):336-43. doi: 10.1038/nature10696. Nature. 2011. PMID: 22113616 Free PMC article.
Neutralizing monoclonal antibodies block human immunodeficiency virus type 1 infection of dendritic cells and transmission to T cells.
Frankel SS, Steinman RM, Michael NL, Kim SR, Bhardwaj N, Pope M, Louder MK, Ehrenberg PK, Parren PW, Burton DR, Katinger H, VanCott TC, Robb ML, Birx DL, Mascola JR. Frankel SS, et al. Among authors: burton dr. J Virol. 1998 Dec;72(12):9788-94. doi: 10.1128/JVI.72.12.9788-9794.1998. J Virol. 1998. PMID: 9811714 Free PMC article.
Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes.
Moulard M, Phogat SK, Shu Y, Labrijn AF, Xiao X, Binley JM, Zhang MY, Sidorov IA, Broder CC, Robinson J, Parren PW, Burton DR, Dimitrov DS. Moulard M, et al. Among authors: burton dr. Proc Natl Acad Sci U S A. 2002 May 14;99(10):6913-8. doi: 10.1073/pnas.102562599. Epub 2002 May 7. Proc Natl Acad Sci U S A. 2002. PMID: 11997472 Free PMC article.
Contrasting IgG structures reveal extreme asymmetry and flexibility.
Saphire EO, Stanfield RL, Crispin MD, Parren PW, Rudd PM, Dwek RA, Burton DR, Wilson IA. Saphire EO, et al. Among authors: burton dr. J Mol Biol. 2002 May 24;319(1):9-18. doi: 10.1016/S0022-2836(02)00244-9. J Mol Biol. 2002. PMID: 12051932
HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites.
Kwong PD, Doyle ML, Casper DJ, Cicala C, Leavitt SA, Majeed S, Steenbeke TD, Venturi M, Chaiken I, Fung M, Katinger H, Parren PW, Robinson J, Van Ryk D, Wang L, Burton DR, Freire E, Wyatt R, Sodroski J, Hendrickson WA, Arthos J. Kwong PD, et al. Among authors: burton dr. Nature. 2002 Dec 12;420(6916):678-82. doi: 10.1038/nature01188. Nature. 2002. PMID: 12478295
660 results