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Novel ATP competitive MK2 inhibitors with potent biochemical and cell-based activity throughout the series.
Oubrie A, Kaptein A, de Zwart E, Hoogenboom N, Goorden R, van de Kar B, van Hoek M, de Kimpe V, van der Heijden R, Borsboom J, Kazemier B, de Roos J, Scheffers M, Lommerse J, Schultz-Fademrecht C, Barf T. Oubrie A, et al. Among authors: borsboom j. Bioorg Med Chem Lett. 2012 Jan 1;22(1):613-8. doi: 10.1016/j.bmcl.2011.10.071. Epub 2011 Nov 3. Bioorg Med Chem Lett. 2012. PMID: 22119462
Discovery of selective and orally available spiro-3-piperidyl ATP-competitive MK2 inhibitors.
Kaptein A, Oubrie A, de Zwart E, Hoogenboom N, de Wit J, van de Kar B, van Hoek M, Vogel G, de Kimpe V, Schultz-Fademrecht C, Borsboom J, van Zeeland M, Versteegh J, Kazemier B, de Roos J, Wijnands F, Dulos J, Jaeger M, Leandro-Garcia P, Barf T. Kaptein A, et al. Among authors: borsboom j. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3823-7. doi: 10.1016/j.bmcl.2011.04.016. Epub 2011 Apr 16. Bioorg Med Chem Lett. 2011. PMID: 21565498
Radial modulation of microbubbles for ultrasound contrast imaging.
Bouakaz A, Versluis M, Borsboom J, de Jong N. Bouakaz A, et al. Among authors: borsboom j. IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Nov;54(11):2283-90. doi: 10.1109/tuffc.2007.532. IEEE Trans Ultrason Ferroelectr Freq Control. 2007. PMID: 18051162
Efficient quantification of the left ventricular volume using 3-dimensional echocardiography: the minimal number of equiangular long-axis images for accurate quantification of the left ventricular volume.
Voormolen MM, Krenning BJ, van Geuns RJ, Borsboom J, Lancée CT, ten Cate FJ, Roelandt JR, van der Steen AF, de Jong N. Voormolen MM, et al. Among authors: borsboom j. J Am Soc Echocardiogr. 2007 Apr;20(4):373-80. doi: 10.1016/j.echo.2006.09.016. J Am Soc Echocardiogr. 2007. PMID: 17400116
Harmonic chirp imaging method for ultrasound contrast agent.
Borsboom JM, Chin CT, Bouakaz A, Versluis M, de Jong N. Borsboom JM, et al. IEEE Trans Ultrason Ferroelectr Freq Control. 2005 Feb;52(2):241-9. doi: 10.1109/tuffc.2005.1406550. IEEE Trans Ultrason Ferroelectr Freq Control. 2005. PMID: 15801312 Free article.
15 results