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Monocytic CCR2(+) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment.
Lesokhin AM, Hohl TM, Kitano S, Cortez C, Hirschhorn-Cymerman D, Avogadri F, Rizzuto GA, Lazarus JJ, Pamer EG, Houghton AN, Merghoub T, Wolchok JD. Lesokhin AM, et al. Among authors: houghton an. Cancer Res. 2012 Feb 15;72(4):876-86. doi: 10.1158/0008-5472.CAN-11-1792. Epub 2011 Dec 15. Cancer Res. 2012. PMID: 22174368 Free PMC article.
Immune rejection of mouse tumors expressing mutated self.
Duan F, Lin Y, Liu C, Engelhorn ME, Cohen AD, Curran M, Sakaguchi S, Merghoub T, Terzulli S, Wolchok JD, Houghton AN. Duan F, et al. Among authors: houghton an. Cancer Res. 2009 Apr 15;69(8):3545-53. doi: 10.1158/0008-5472.CAN-08-2779. Epub 2009 Apr 7. Cancer Res. 2009. PMID: 19351857 Free PMC article.
Strategies to overcome immune ignorance and tolerance.
Perales MA, Blachere NE, Engelhorn ME, Ferrone CR, Gold JS, Gregor PD, Noffz G, Wolchok JD, Houghton AN. Perales MA, et al. Among authors: houghton an. Semin Cancer Biol. 2002 Feb;12(1):63-71. doi: 10.1006/scbi.2001.0397. Semin Cancer Biol. 2002. PMID: 11926414 Review.
251 results