Christians U - Search Results

1

Influence of SLCO1B1 polymorphisms on the drug-drug interaction between darunavir/ritonavir and pravastatin.

Aquilante CL, Kiser JJ, Anderson PL, Christians U, Kosmiski LA, Daily EB, Hoffman KL, Hopley CW, Predhomme JA, Schniedewind B, Sidhom MS. Aquilante CL, et al. Among authors: christians u. J Clin Pharmacol. 2012 Nov;52(11):1725-38. doi: 10.1177/0091270011427907. Epub 2011 Dec 14. J Clin Pharmacol. 2012. PMID: 22174437 Clinical Trial.

2

Randomized, double-blind, placebo-controlled, single intravenous dose-escalation study to evaluate the safety, tolerability, and pharmacokinetics of the novel coronary smooth muscle cell proliferation inhibitor Biolimus A9 in healthy individuals.

Steudel W, Dingmann C, Zhang YL, Bendrick-Peart J, Clavijo C, Shulze J, Betts R, Christians U. Steudel W, et al. Among authors: christians u. J Clin Pharmacol. 2011 Jan;51(1):29-39. doi: 10.1177/0091270010361255. Epub 2010 Mar 19. J Clin Pharmacol. 2011. PMID: 20305057 Clinical Trial.

3

Continuous administration of a selective alpha7 nicotinic partial agonist, DMXBA, improves sensory inhibition without causing tachyphylaxis or receptor upregulation in DBA/2 mice.

Stevens KE, Cornejo B, Adams CE, Zheng L, Yonchek J, Hoffman KL, Christians U, Kem WR. Stevens KE, et al. Among authors: christians u. Brain Res. 2010 Sep 17;1352:140-6. doi: 10.1016/j.brainres.2010.06.063. Epub 2010 Jul 3. Brain Res. 2010. PMID: 20599427 Free PMC article.

4

Toxicodynamic effects of ciclosporin are reflected by metabolite profiles in the urine of healthy individuals after a single dose.

Klawitter J, Haschke M, Kahle C, Dingmann C, Klawitter J, Leibfritz D, Christians U. Klawitter J, et al. Among authors: christians u. Br J Clin Pharmacol. 2010 Aug;70(2):241-51. doi: 10.1111/j.1365-2125.2010.03689.x. Br J Clin Pharmacol. 2010. PMID: 20653677 Free PMC article. Clinical Trial.

5

A sensitive assay for the quantification of morphine and its active metabolites in human plasma and dried blood spots using high-performance liquid chromatography-tandem mass spectrometry.

Clavijo CF, Hoffman KL, Thomas JJ, Carvalho B, Chu LF, Drover DR, Hammer GB, Christians U, Galinkin JL. Clavijo CF, et al. Among authors: christians u. Anal Bioanal Chem. 2011 May;400(3):715-28. doi: 10.1007/s00216-011-4775-z. Epub 2011 Mar 12. Anal Bioanal Chem. 2011. PMID: 21400080

6

Structural identification of SAR-943 metabolites generated by human liver microsomes in vitro using mass spectrometry in combination with analysis of fragmentation patterns.

Strom T, Shokati T, Klawitter J, Klawitter J, Hoffman K, Schiebel HM, Christians U. Strom T, et al. Among authors: christians u. J Mass Spectrom. 2011 Jul;46(7):615-24. doi: 10.1002/jms.1930. J Mass Spectrom. 2011. PMID: 21671437

7

A high-throughput U-HPLC-MS/MS assay for the quantification of mycophenolic acid and its major metabolites mycophenolic acid glucuronide and mycophenolic acid acyl-glucuronide in human plasma and urine.

Klepacki J, Klawitter J, Bendrick-Peart J, Schniedewind B, Heischmann S, Shokati T, Christians U, Klawitter J. Klepacki J, et al. Among authors: christians u. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Feb 1;883-884:113-9. doi: 10.1016/j.jchromb.2011.07.021. Epub 2011 Aug 2. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 21839692 Free PMC article.

8

A low blood volume LC-MS/MS assay for the quantification of fentanyl and its major metabolites norfentanyl and despropionyl fentanyl in children.

Clavijo CF, Thomas JJ, Cromie M, Schniedewind B, Hoffman KL, Christians U, Galinkin JL. Clavijo CF, et al. Among authors: christians u. J Sep Sci. 2011 Dec;34(24):3568-77. doi: 10.1002/jssc.201100422. Epub 2011 Sep 13. J Sep Sci. 2011. PMID: 21916010

9

Everolimus and sirolimus in combination with cyclosporine have different effects on renal metabolism in the rat.

Bohra R, Schöning W, Klawitter J, Brunner N, Schmitz V, Shokati T, Lawrence R, Arbelaez MF, Schniedewind B, Christians U, Klawitter J. Bohra R, et al. Among authors: christians u. PLoS One. 2012;7(10):e48063. doi: 10.1371/journal.pone.0048063. Epub 2012 Oct 31. PLoS One. 2012. PMID: 23118926 Free PMC article.

10

Concentration of tacrolimus and major metabolites in kidney transplant recipients as a function of diabetes mellitus and cytochrome P450 3A gene polymorphism.

Chitnis SD, Ogasawara K, Schniedewind B, Gohh RY, Christians U, Akhlaghi F. Chitnis SD, et al. Among authors: christians u. Xenobiotica. 2013 Jul;43(7):641-9. doi: 10.3109/00498254.2012.752118. Epub 2013 Jan 2. Xenobiotica. 2013. PMID: 23278282 Free PMC article.

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